摘要
目的探讨微创唇部小唾液腺活检技术应用于干燥综合征患者诊断中的安全性和价值。方法观察131例拟诊干燥综合征的患者实施微创唇部小唾液腺活检术后的近期及远期并发症及患者对于该项技术的耐受性和接受程度,观察标本合格率。结果标本合格率为98. 5%,术后4小时疼痛VAS评分为(3±0. 6),无1例发生术后出血。术后24小时观察91%(119/131)患者切口完全愈合,9%(12/131)患者形成浅表溃疡,无1例术后感染,98. 5%(129/131)的患者表示微创唇小唾液腺活检技术是可以接受的。术后30天115例患者完成了远期随访。无1例唇腺囊肿发生,无1例瘢痕形成,有2例(1. 5%)患者遗留有轻度感觉异常。结论微创唇小唾液腺活检技术创伤小,无需缝合拆线,方法简易,术后并发症少,患者接受程度良好,取得标本符合病理检查需要。适合在临床推广。
Objective To evaluate the safety and value of the technique for minimally invasive minor salivary gland biopsy(MSGB) in the lip in the diagnosis of Sjogren’s syndrome( SS).Methods 131 patients suspected for SS who undergo minimally invasive minor salivary glandbiopsy.Observe Short-term and long-term postoperative complications and patients tolerance and acceptance of the technique.Observe the qualified rate of the sample.Results The qualified rate of the sample was 98. 5%.The VAS of 4 hours after the operation was( 3±0. 6),no patient postoperative bleeding.Complete healing of incision 24 hours after operationin 91%( 119/131) patients.9%( 12/131) patients formed superficial ulcers. No postoperative infection.98. 5%( 129/131) patients indicate that minimally invasive biopsy of minor salivary glands is acceptable.115 patients were followed up 30 days after the operation.No 1 cases of lip glandular cysts were found,and no scar formation were found.There were 2 cases( 1. 5%) of patients with mild sensory abnormalities.Conclusion Minimally invasive lip minor salivary gland biopsy is a minimally invasive technique without stitching and suture removal.The method is simple and has less postoperative complications.The patient is well received.The sample is meet the requirement of pathological examination.It is suitable for clinical application.
作者
赵嘉英
黄松涛
李青
严宏莉
陈立华
胡倩
陈飞
Zhao Jiaying;Huang Songtao;Li Qing(Guang an People's Hospital,Guang an,Sichuan 638500,China)
出处
《四川医学》
CAS
2019年第7期711-714,共4页
Sichuan Medical Journal
基金
广安市科技创新基金(编号:201842)
关键词
小唾液腺活检术
干燥综合征
诊断
minor salivary gland biopsy
Sjogren’s syndrome
diagnosis