摘要
冠状动脉无复流现象(NRP)指心外膜血运重建成功后冠状动脉远端前向血流速度变慢或无血流而导致的大部分心肌组织得不到有效灌注。由于检测手段及定义不同,因此关于NRP发生率目前的研究报道不一,据统计,急性心肌梗死(AMI)患者选择性经皮冠状动脉介入治疗(PCI)中NRP发生率为0.6%~6.0%,急诊PCI中NRP发生率为10.0%~50.0%。NRP是心肌梗死、住院期间死亡及远期主要不良心血管事件(MACE)的独立预测因子,因此明确NRP的预测指标并制定有效的防治策略对减少AMI患者PCI后NRP的发生及死亡具有重要意义。本文主要综述了AMI患者PCI中NRP的预测指标及防治策略,为有效减少NRP的发生提供参考。
Coronary artery no-reflow phenomenon(NRP)means lack of adequate perfusion in massive myocardial tissues due to slow forward blood flow velocity or no blood flow of distal coronary artery after successful epicardial revascularization.As different detection means and definitions,there are different reports about the incidence of NRP;according to the statistics,incidence of NRP is 0.6% to 6.0% in selective percutaneous coronary intervention(PCI)and 10.0% to 50.0%in emergency PCI for acute myocardial infarction(AMI).NRP is one of independent predictors of myocardial infarction,in-hospital mortality and long-term MACE,thus it is of great significance to clear and definite the predictors,preventive and therapeutic strategies,reduce the incidence of NRP and death in AMI patients undergoing PCI.This paper mainly reviewed the predictors,preventive and therapeutic strategies of NRP in AMI patients undergoing PCI,in order to provide a reference for effectively reducing the risk of NRP.
作者
赵倩
赵刚
ZHAO Qian;ZHAO Gang(Chongqing Medical University,Chongqing 401331,China;University Town Hospital Affiliated to Chongqing Medical University,Chongqing 401331,China)
出处
《实用心脑肺血管病杂志》
2019年第7期1-4,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
心肌梗死
无复流现象
血管成形术
气囊
冠状动脉
经皮冠状动脉介入治疗
预测
病症防治
综述
Myocardial infarction
No-reflow phenomenon
Angioplasty,balloon,coronary
Percutaneous coronary intervention
Forecasting
Disease treating and preventing
Review
