摘要
目的探讨宫腔镜下电切术联合刮宫术治疗多发性子宫内膜息肉(EMP)患者的临床疗效。方法80例多发性子宫内膜息肉患者,根据随机数字表法分为对照组和研究组,每组40例。对照组患者接受宫腔镜下电切术治疗,研究组患者接受宫腔镜下电切术联合刮宫术治疗。观察比较两组患者的手术时间、术中出血量、住院时间;随访6个月,比较两组的复发率;分别在术前、术后3 d检测并比较两组患者的免疫指标水平。结果随访6个月,研究组患者复发率为5%(2/40),明显低于对照组的35.00%(14/40),差异有统计学意义(χ2=11.2500, P=0.0008<0.05)。研究组患者的手术时间(24.02±1.21)min明显长于对照组的(18.52±1.20)min,差异有统计学意义(P<0.05)。两组患者的术中出血量及住院时间比较差异均无统计学意义(P>0.05)。术前,两组患者免疫球蛋白(Ig)G、IgM、IgA水平比较差异均无统计学意义(P>0.05)。术后3 d,研究组患者的IgG、IgA水平明显高于对照组,差异均有统计学意义(P<0.05);两组患者的IgM水平比较差异无统计学意义(P>0.05)。结论宫腔镜下电切术联合刮宫术治疗多发性子宫内膜息肉的疗效显著,安全且高效,能够明显改善免疫功能指标,疾病复发率低,值得临床推广应用。
Objective To discuss the clinical efficacy of hysteroscopic electrotomy combined with curettage in the treatment of multiple endometrial polyps(EMP) patients. Methods A total of 80 multiple endometrial polyps patients were divided by random number table method into control group and research group, with 40 cases in each group. The control group was treated with hysteroscopic electrotomy, and the research group was treated with hysteroscopic electrotomy combined with currettage. Observation and comparison were made on operation time, amount of intraoperative hemorrhage, hospitalization time and recurrence rate after 6 months of follow-up in two groups. Immune indexes of the two groups were detected and compared before operation and 3 d after operation. Results After 6 months of follow-up the research group had obviously lower recurrence rate as 5%(2/40) than 35.00%(14/40) in the control group, and the difference was statistically significant(χ2=11.2500, P=0.0008<0.05). The research group had obviously longer operation time as(24.02±1.21) min than(18.52± 1.20) min in the control group, and the difference was statistically significant(P<0.05). There was no statistically significant difference in amount of intraoperative hemorrhage and hospitalization time between the two groups(P>0.05). There was no statistically significant difference in immunoglobulin(Ig) G, IgM, IgA before operation between the two groups(P>0.05). At 3 d after operation, the research group had obviously higher IgG and IgA than the control group, and the difference was statistically significant(P<0.05). There was no statistically significant difference in IgM level between the two groups(P>0.05). Conclusion Hysteroscopic electrotomy combined with curettage shows remarkable efficacy in the treatment of multiple endometrial polyps. It is safe and effective, and can significantly improve immune function indicators, lower recurrence rate of disease. It is worthy of clinical promotion and application.
作者
石慧芬
杨兆林
汪莉
陈倩莹
SHI Hui-fen;YANG Zhao-lin;WANG Li(Department of Gynaecology,Guangdong Provincial People’s Hospital Nanhai Hospital (Foshan Nanhai District Second People’s Hospital),Foshan 528251,China)
出处
《中国现代药物应用》
2019年第14期19-21,共3页
Chinese Journal of Modern Drug Application
