摘要
舒更葡糖(SUG)是一种新型非去极化肌松药拮抗药,对罗库溴铵和维库溴铵等甾体类非去极化肌松药物具有特异性的快速的拮抗作用,其效果优于乙酰胆碱酯酶抑制剂。可用于合并脏器功能障碍、重症肌无力、困难气道以及特殊人群等患者。本文对其作用机制、药代动力学特点、临床应用及安全性和不良反应进行综述。
Sugammadex(SUG)is a new type of non-depolarizing muscle relaxant antagonist,which has a specific and rapid antagonistic effect on steroidal non-depolarizing muscle relaxants such as rocuronium and vecuronium,and its effect is better than that of acetylcholinesterase inhibitors.It can be used in patients with organ dysfunction,myasthenia gravis,difficult airway or special groups of patients.The mechanism,pharmacokinetic characteristics,clinical application,safety and adverse reactions of SUG are reviewed in this paper.
作者
李凯
赵国庆
李亮
LI Kai;ZHAO Guoqing;LI Liang(Department of Anesthesiology,China-Japan Union Hospital of Jilin University,Changchuan 130021,China)
出处
《麻醉安全与质控》
2019年第4期236-239,共4页
Perioperative Safety and Quality Assurance
基金
吴阶平医学基金会(320.6750.18187)
吉林省发改委项目(2018C020)
关键词
SUG
肌松药拮抗药
SUG
muscle relaxant antagonist
