摘要
[目的]阐明何首乌传统炮制工艺九蒸九晒过程中多成分含量变化的科学内涵。[方法]采用传统的黑豆共蒸法进行九蒸九晒,并首次监测炮制过程中多成分的含量变化。[结果]随着何首乌蒸晒次数的增加,浸出物、二苯乙烯苷含量呈明显的下降趋势,游离蒽醌含量则显著上升;多成分含量测定中,没食子酸呈现先上升后下降,儿茶素、二苯乙烯苷含量逐渐减少,大黄素、大黄素甲醚呈缓慢上升趋势,5-羟甲基糠醛含量变化不明显。[结论]何首乌九蒸九晒过程中性状及各成分含量变化规律明显,可为何首乌的炮制提供理论依据和工艺参考。
[Objective] The research aimed to clarify the scientific connotation of the change of multi-component content in the processing technology of nine-time repeat of the steaming and sun-drying (NRSSP) of Polygonum multiflorum.[Methods] To steam with black beans and NRSSP,and for the first time monitoring the change of multi-component content during processing.[Results] With the increase of steaming times of Polygonum multiflorum ,the contents of alcohol soluble extract and stilbene glycoside showed a significant downward trend,the content of free anthraquinones increased significantly;in the determination of multi-component content,gallic acid first increased and then decreased,the content of catechin and stilbene glucoside decreased gradually,the content of emodin and physcion slowly increased,the change of the content of 5-hydroxymethylfurfural was not obvious.[Conclusion]The rules of characteristics and contents of the main components in the processing technology of NRSSP of Polygonum multiflorum are obvious,it can provide a theoretical basis and process reference for the processing.
作者
路丽
张洪坤
林钦贤
黄玉瑶
吴韶辉
潘林燕
高贯彪
LU Li;ZHANG Hong-kun;LIN Qin-xian(Bozhou Huqiao Pharmaceutical Industy Co.,Ltd.,Bozhou,Anhui 236800;Guangzhou Zhongzhiyuan Chinese Medicine Co.,Ltd.,Guangzhou,Guangdong 510925;Xiangxue Pharmaceutical Co.,Ltd.,Guangzhou,Guangdong 510663)
出处
《安徽农业科学》
CAS
2019年第15期177-182,共6页
Journal of Anhui Agricultural Sciences
基金
国家中医药管理局中药标准化项目(ZYBZH-Y-AH-03)
关键词
何首乌
九蒸九晒
炮制工艺
多成分含量
变化规律
Polygonum multiflorum
Nine-time repeat of the steaming and sun-drying
Processing technology
Multi-component content
Variation law
