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甲胎蛋白在肝细胞肝癌中的应用研究进展 被引量:6

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摘要 甲胎蛋白(AFP)是一种单链糖蛋白,也是一种胚胎性相关蛋白。胎儿肝脏是合成AFP的主要场所,胎儿出生18个月后其水平逐渐下降,且健康成人血清中AFP水平一般低于10 μg/L。肝细胞癌变条件下,低甲基化作用会使AFP基因重新表达。肝细胞肝癌是临床上最常见的恶性肿瘤之一,其发病率在全世界范围的恶性肿瘤中位于第6位,在我国位于第4位,且全球肿瘤相关致死率与我国相同,均位于第3位。
作者 姜楷 陈伟庆
出处 《现代医药卫生》 2019年第15期2344-2347,共4页 Journal of Modern Medicine & Health
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