摘要
目的分析慢性心力衰竭(CHF)住院患者发生心肾综合征(CRS)的临床特点及相关危险因素。方法选取147例CHF患者,根据eGFR值是否<60 mL/(min·1.73 m^2)分为CHF组65例和CRS组82例,收集患者一般临床资料及化验检查指标,采用Logistic回归对CHF伴发CRS的危险因素进行单因素和多因素分析。结果两组患者在年龄、性别、心功能分级、高血压病史方面差异均有统计学意义(P<0.05或P<0.01)。CRS组患者血Hb、LVEF水平明显降低,PLT、UA、血脂、左室壁厚度明显增加,与CHF组比较差异具有显著性统计学意义(P<0.05或P<0.01)。Logistic回归显示,高龄、女性、高血压病史、入院时PLT、LDL-C、UA升高,LVEF值降低是CHF发生CRS的高危因素。结论高龄、女性、高血压病史、入院时PLT、UA、LDL-C水平升高、LVEF值降低的CHF患者容易发生CRS。
Objective:To analyze the clinical characteristics and related risk factors of CRS in CHF inpatients.Methods:147 patients were divided into CHF group(65 cases)and CRS group(82 cases),according to whether e GFR value was<60 mL/(min/1.73 m^2).The general clinical data and laboratory indices of patients were collected.The risk factors of CRS associated with CHF were analyzed by logistic regression.Results:There were significant differences in age,sex,heart function classification and history of hypertension between the two groups(P<0.05 or P<0.01).The levels of serum Hb and LVEF in CRS group were significantly decreased;PLT,UA,blood lipid and left ventricular wall thickness were significantly increased,and there was significant difference between CRS group and CHF group(P<0.05 or P<0.01).Logistic regression showed that elderly,female,history of hypertension,increased levels of PLT,LDL-C and UA at admission and decreased LVEF were high risk factors for CRS in CHF.Conclusion:CRS is prone to occur in elderly,female,history of hypertension,increased levels of PLT,UA and LDL-C and decreased LVEF in CHF patients at admission.
作者
吴华芹
张并璇
李雨濛
杨阳柳林
赵畅
宋庆桥
Wu Huaqin;Zhang Bingxuan;Li Yumeng(Guang′anmen Hospital,China Academy of Chinese Medical Science,Beijing 100053,China.)
出处
《中国中医急症》
2019年第7期1139-1142,共4页
Journal of Emergency in Traditional Chinese Medicine
基金
国家自然科学基金项目(81573799)
关键词
心力衰竭
心肾综合征
危险因素
Chronic heart failure
Cardio-renal syndrome
Risk factors
