摘要
目的:为抗菌药物监管提供相关分析数据,分析评价某肿瘤专科医院2017年Ⅰ类切口手术围手术期预防用抗菌药物情况。方法:对本院2017年期间抽取的共计300例清洁手术病历进行回顾性研究,针对其围手术期抗菌药物预防使用信息以及相关药物成本-效果比等数据进行统计、对比分析。结果:2017年Ⅰ类切口手术围手术期间抗菌药物使用率约为 16.33%;49例使用抗菌药物病历中,以头孢唑林( 55.11%)、头孢呋辛( 28.57%)预防使用为主;预防用抗菌药物DUI值均≤1,单日用药剂量合理;不合理预防用药主要表现在“预防给药品种不适宜”,占总不合理率的 63.64%。结论:从药物经济性角度考虑,头孢唑林是较好的清洁手术围手术期预防性抗菌用药方案。
AIM : To analyze the surgical antimicrobial prophylaxis and to evaluate the effectiveness of different antimicrobial solutions about type Ⅰ incision operation in a cancer hospital. METHODS : Three-hundred cases of clean surgery in our hospital from January to December in 2017 were involved and the data of the surgical antimicrobial prophylaxis were retrospective collected and evaluated.The cost-effectiveness analysis method was applied to compare the ratio of cost to effectiveness between the three solutions. RESULTS :The utilization ratio of antibiotics in clean surgery was 16.33%, which met the hospital requirements. Cefazolin ( 55.11%) and Cefuroxime ( 28.57%) were mainly preventive use in the 49 cases of antibiotics. DUI values of antibiotics for prophylaxis were ≤1, antibiotics dosage for single day was reasonable. The inappropriate use of antibiotics was mainly manifested in “unsuitable varieties”, which accounted for 63.64% of the total irrational rate. CONCLUSION : From the perspective of ecnnomic medication, the preoperative uses of cefazolin in patients treated with clean surgery was a better option.
作者
杨静谟
张波
孙言才
YANG Jingmo;ZHANG Bo;SUN Yancai(Anhui Provincial Cancer Hospital,Hefei 230001,Anhui,China;The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Sciences and Technology of China,Hefei 230001,Anhui,China)
出处
《中国临床药理学与治疗学》
CAS
CSCD
2019年第7期821-825,共5页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
清洁手术
围手术期
抗菌药物
合理用药
成本-效果分析
type Ⅰ incision operation
perioperative period
antibiotics
rational drug use
cost-effectiveness analysis
