摘要
目的探讨2型糖尿病患者血清CA199、CEA水平与其血糖水平之间的关系。方法选取东莞市寮步医院2015年5月-2018年5月收治的100例2型糖尿病患者作为观察组,选择同期入院体检的96例健康者作为对照组,分析2型糖尿病患者血清CA199、CEA水平与血糖水平之间的相关性。结果观察组空腹血糖、餐后2h血糖和糖化血红蛋白以及血清CA199、CEA水平均高于对照组,差异均具有统计学意义(P<0.05).相关分析结果显示,血清CA199、CEA水平与患者空腹血糖、餐后2h血糖和糖化血红蛋白水平呈正相关(P<0.05)。结论2型糖尿病患者血清CA199和CEA水平异常高于健康人群,而且其水平与血糖各项指标呈正相关,可作为除恶性肿瘤之外临床判定2型糖尿病的指标。
Objective To discuss the relationship between the levels of CA199 and CEA with blood glucose in patients with type 2 diabetes mellitus. Methods A total of 100 patients with type 2 diabetes mellitus in Liaobu Hospital of Dongguan City from May 2015 to May 2018 were selected as observation group, 96 healthy subjects in the same period were selected as control group. The levels of blood glucose, CA199 and CEA were detected and the correlation was analyzed. Results The levels of FPG, 2 h PG, GHbA1, CA199 and CEA were significantly higher than control group (P<0.05). The Spearman analysis showed that the levels of CA199 and CEA were positively correlated with the levels of FPG, 2 h PG and GHbA1 in observation group (P<0.05). Conclusion The levels of CA199 and CEA in type 2 diabetes mellitus patients were higher than healthy person, which were positively correlated with the blood glucose indexes, and it could be used as a potential marker for type 2 diabetes mellitus besides malignant tumors.
作者
黄业灿
张婷容
黄永煜
马和平
戴永清
HUANG Yecan;ZHANG Tingrong;HUANG Yongyu;MA Heping;DAI Yongqing(Out-patient Department,Liaobu Hospital of Dongguan City,Dongguan 523400,Guangdong Province,China)
出处
《中国实用乡村医生杂志》
2019年第7期58-60,共3页
Chinese Practical Journal of Rural Doctor
