摘要
目的分析重症肝炎患者并发肝性脑病(HE)的危险因素。方法我院收治的200例重症肝炎患者,根据是否发生HE分为HE组和非HE组,比较两组临床资料,分析重症肝炎患者并发HE的危险因素。结果 200例重症肝炎患者中并发HE者68例,HE发生率为34. 00%。HE组合并自发性腹膜炎、上消化道出血、肺部感染比例及国际标准化比值、白细胞计数、甲胎蛋白、血钠、血氨、总胆红素、甘油三酯与非HE组比较,差异有统计学意义(P<0. 05);合并自发性腹膜炎、合并上消化道出血、合并肺部感染、高国际标准化比值、低血钠、高血氨、高总胆红素是重症肝炎患者并发HE的危险因素(P<0. 05)。结论重症肝炎患者并发HE比例较高,合并自发性腹膜炎、合并上消化道出血、合并肺部感染、高国际标准化比值、低血钠、高血氨、高总胆红素是其危险因素,需针对性给予早期处理。
Objective To analyze the risk factors for hepatic encephalopathy(HE) in patients with severe hepatitis.Methods Two hundred patients with severe hepatitis in our hospital were divided into HE group and non-HE group according to whether HE occurred or not.The clinical data were compared between the two groups,and the risk factors for HE in the patients with severe hepatitis were analyzed.Results Among the 200 patients,68 cases were complicated with HE,and the incidence rate of HE was 34. 00%.There were significant differences in the combined spontaneous peritonitis,combined upper gastrointestinal bleeding,combined pulmonary infection,international normalized ratio,white blood cell count,alpha-fetoprotein,blood sodium,blood ammonia,total bilirubin and triglyceride between the two groups(P < 0. 05). We found that combined spontaneous peritonitis,combined upper gastrointestinal bleeding,combined pulmonary infection,high international normalized ratio,low blood sodium,high blood ammonia and high total bilirubin were risk factors for patients with severe hepatitis complicated HE(P<0. 05).Conclusion Patients with severe hepatitis have a high proportion of HE.Combined spontaneous peritonitis,combined upper gastrointestinal bleeding,combined pulmonary infection,high international normalized ratio,low blood sodium,high blood ammonia and high total bilirubin are risk factors.Therefore,it is necessary to give targeted early treatment.
作者
刘梦
严超
罗凤莲
LIU Meng;YAN Chao;LUO Feng-lian(Department of Infectious Diseases,The First Affiliated Hospital,Chengdu Medical College,Chengdu 610500,China)
出处
《实用医院临床杂志》
2019年第4期108-110,共3页
Practical Journal of Clinical Medicine
关键词
重症肝炎
肝性脑病
危险因素
Severe hepatitis
Hepatic encephalopathy
Risk factors
