摘要
目的观察代谢手术后的肥胖型2型糖尿病患者在低碳水化合物饮食干预下的体重反弹情况。方法将2010年1月至2015年11月期间在长海医院行代谢手术的38例患者根据随机数字表法分为两组,比较行低碳水化合物(LC)饮食或糖尿病(DM)饮食干预后血糖水平、体重反弹情况。结果 DM饮食干预组空腹血糖、糖化血红蛋白、空腹C肽、体重、腰围、BMI等干预前后的差值无统计学意义(t=0.34,S=1.00~32.5,P值均>0.05);LC饮食干预组空腹血糖、体重、腰围、BMI等干预前后的差值有统计学意义(t=2.38,S=17~24.5,P值均<0.05)。两组间比较:体重差值(Z=2.31, P<0.05)、BMI差值(Z=2.36, P<0.05)、体重反弹率的差异(P<0.05)有统计学意义,LC饮食干预组更有优势。结论代谢手术后予低碳水化合物饮食干预可改善肥胖型2型糖尿病患者空腹血糖及肥胖指标(体重、腰围、BMI);与糖尿病饮食干预比较,予低碳水合化物饮食管理,可更显著改善BMI下降幅度,减少体重反弹率及反弹幅度,能更有效控制体重反弹。
Objective To observe the improvement of weight rebound in obese type 2 diabetes mellitus patients who underwent metabolic surgery after low-carbohydrate diet intervention. Methods 38 patients with obese type 2 diabetes mellitus who had underwent metabolic surgery in Changhai Hospital from Jan. 2010 to Nov. 2015, were randomly divided into two groups and intervened by low carbohydrate (LC) diet or diabetes mellitus (DM) diet. The blood glucose and body weight of the two groups were compared and analyzed. Results There was no statistical difference in fasting blood glucose, HbA1c, fasting C-peptide, body weight, waistline and BMI value (t=0.34, S=1.00-32.5, P>0.05) in diabetes mellitus diet intervention group;while there was significant statistical difference in fasting blood glucose, body weight, waistline and BMI (t=2.38, S=17-24.5, P<0.05) in low-carbohydrate diet intervention group. There was significant differences in body weight difference (Z=2.31, P<0.05), BMI difference (Z=2.36, P<0.05), and weight rebound rate (P<0.05) between the two groups, with the low carbohydrate diet intervention group displaying advantages. Conclusions Low carbohydrate diet intervention can improve fasting blood glucose, obesity indexes in obese type 2 diabetes mellitus patients who underwent metabolic surgery. Compared with diabetes mellitus diet intervention, low carbohydrate diet intervention can more greatly improve weight, weight rebound rate, rebound scale and have more advantages for maintaining the operation effects.
作者
韩莉
王燕
邹大进
Han Li;Wang Yan;Zou Dajin(Department of Endocrinology, People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang 830000, China;The Diagnosis and Treatment Center of Obesity and Diabetes, Changhai Hospital, the Second Military Medical Uni-versity, Shanghai 200433, China)
出处
《中华内分泌外科杂志》
CAS
2019年第3期191-194,共4页
Chinese Journal of Endocrine Surgery