摘要
目的:探讨空腹血糖(FPG)、餐后2h血糖(2hPG)指导下胰岛素皮下注射治疗高龄妊娠期糖尿病(GDM)患者的效果及对妊娠结局的影响。方法:选取2017年1月-2018年10月笔者所在医院收治的80例高龄GDM患者为对象,按照入院单双顺序分为对照组(n=40)和观察组(n=40),对照组采用常规运动和饮食疗法进行治疗,观察组在FPG、2hPG指导下采用皮下注射胰岛素进行治疗,比较两组临床效果和妊娠结局。结果:治疗后,观察组的FPG、2hPG、HbA1c水平均显著低于对照组(P<0.05);治疗后,观察组早产、新生儿低血糖、新生儿畸形、新生儿急性呼吸窘迫综合征及产后出血发生率均显著低于对照组(P<0.05)。结论:FPG、2hPG指导下胰岛素皮下注射能够有效控制高龄GDM患者血糖水平,改善妊娠结局。
Objective:To investigate the effect of insulin subcutaneous injection under the guidance of fasting plasma glucose(FPG) and postprandial 2 hour plasma glucose(2 h PG) in the treatment of gestational diabetes mellitus(GDM) in the elderly and its influence on pregnancy outcome.Method:80 elderly patients with GDM admitted to our hospital from January 2017 to October 2018 were selected and divided into the control group(n=40) and the observation group(n=40)according to the order of admission.The control group was treated with routine exercise and diet therapy.The observation group was treated with subcutaneous injection of insulin under the guidance of FPG and 2 h PG.The clinical efficacy and pregnancy outcomes of the two groups were compared.Result:After treatment,the levels of FPG,2 h PG and HbA1 c in the observation group were significantly lower than those in the control group(P<0.05).After treatment,the incidence of premature delivery,neonatal hypoglycemia,neonatal malformation,neonatal acute respiratory distress syndrome and postpartum hemorrhage in the observation group were significantly lower than those in the control group(P<0.05).Conclusion:Insulin subcutaneous injection under the guidance of FPG and 2 h PG can effectively control the blood sugar level of elderly GDM patients and improve pregnancy outcomes.
作者
王芳
WANG Fang(First-author’s address:Zaoyang Maternal and Child Health Hospital,Zaoyang 441200,China)
出处
《中外医学研究》
2019年第16期107-109,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
