摘要
目的:观察药学干预对儿科抗菌药物合理使用的影响。方法:选取接受抗菌药物治疗的100例患儿作为观察对象。采用随机数字表法将其分为观察组和对照组各50例。对照组给予常规用药指导,观察组在对照组基础上给予药学干预。比较两组抗菌药物使用情况(适应证不当、用法用量不当、药物选择不当)、治疗效果、不良反应发生率及家属满意度。结果:观察组在适应证不当、用法用量不当、药物选择不当等方面的发生率均明显低于对照组,差异具有统计学意义(P<0.05)。观察组治疗总有效率为92.0%(46/50),明显高于对照组的72.0%(36/50),差异具有统计学意义(P<0.05)。观察组不良反应发生率为6.0%(3/50),明显低于对照组的24.0%(12/50),差异具有统计学意义(P<0.05)。观察组家属满意度为96.0%(48/50),明显高于对照组的80.0%(40/50),差异具有统计学意义(P<0.05)。结论:儿科使用抗菌药物的过程中加强药学干预,能提升抗菌药物的使用合理性,保证疗效,减少不良反应,提高家属满意度。
Objective: To observe effects of pharmaceutical intervention on rational use of pediatric antibacterial agents. Methods: 100 children treated with the antibacterial agents were selected as the subjects. They were divided into observation group (n=50) and control group (n=50) by using the random number table method. The control group was given the regular medication guidance, while the observation group was given the pharmacological intervention on the basis of that of the control group. The use of the antibacterial agents (inappropriate indications, improper usage, and inappropriate drug selection), treatment effects, incidence of adverse reactions, and family satisfaction were compared between the two groups. Results: The incidences of the inappropriate indications, the improper usage and the inappropriate drug selection in the observation group were significantly lower than those in the control group, and the differences were statistically significant (P<0.05). The total effective rate of the observation group was 92.0%(46/50), which was significantly higher than that of the control group (72.0%, 36/50), and the difference was statistically significant (P<0.05). The incidence of adverse reactions in the observation group was 6.0%(3/50), which was significantly lower than that in the control group (24.0%, 12/50), and the difference was statistically significant (P<0.05). The family satisfaction in the observation group was 96.0%(48/50), which was significantly higher than that in the control group (80.0%, 40/50), and the difference was statistically significant (P<0.05). Conclusions: Pharmaceutical intervention in the use of the pediatric antibacterial agents can improve the rational use of the agents, ensure the effects, reduce the adverse reactions, and improve the family satisfaction.
作者
荆宁宁
JING Ningning(Children’s Hospital Affiliated to Zhengzhou University,Henan children’s Hospital,Zhengzhou children’s Hospital,Zhengzhou 450000 Henan,China)
出处
《中国民康医学》
2019年第10期133-135,共3页
Medical Journal of Chinese People’s Health
关键词
儿科
抗菌药物
药学干预
Pediatrics
Antibacterial agent
Pharmaceutical intervention
