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中性粒细胞/淋巴细胞比值与帕金森合并周围神经病变的相关性分析 被引量:6

Correlation between neutrophil/lymphocyte ratio and Parkinson’s disease with peripheral neuropathy
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摘要 目的中性粒细胞/淋巴细胞比值(NLR)与帕金森病(PD)合并周围神经病变之间的关系。方法对97例患者进行肌电图检查,其中38例合并周围神经病的帕金森病患者为病例组;59例不合并周围神经病的帕金森病患者为对照组。检测两组患者血常规,记录中性粒细胞及淋巴细胞计数,计算中性粒细胞/淋巴细胞比值,并记录患者的性别、年龄、病程及Hoehr-Yahr(H-Y)分级,比较各因素在两组之间的差异。结果病例组中性粒细胞/淋巴细胞比值均高于对照组(P<0.05),病例组及对照组性别、年龄、帕金森病程无明显差异(P>0.05)。结论中性粒细胞/淋巴细胞比值升高可能是帕金森周围神经损害的危险因素。 Objective To analyzed the relationship between Neutrophil/Lymphocyte Ratio(NLR)and Parkinson’s disease(PD)with peripheral neuropathy.Methods Electromyography was performed in 97 patients,among which 38 patients with Parkinsons disease with peripheral neuropathy were the case group;59 patients with Parkinson’s disease without peripheral neuropathy were the control group.The blood routine of the two groups was performed,the neutrophil and lymphocyte counts were recorded,and the neutrophil/lymphocyte ratio was calculated.The gender,age,duration of disease,and Hoehr-Yahr(HY)grading were recorded,and the factors were compared.The difference between the two groups were analyzed.Results The neutrophil/lymphocyte ratio in the case group was higher than thatin the control group(P<0.05).There was no significant difference in the sex,age,Parkinson’s disease courses between the case group and the control group(P>0.05).Conclusion The elevated neutrophil/lymphocyte ratio may be a risk factor for peripheralnerve damage in Parkinson’s disease.
作者 杨小英 杨新玲 徐军伟 YANG Xiaoying;YANG Xinling;XU Junwei(Department of Neurology,Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830028,China)
出处 《中风与神经疾病杂志》 CAS 2019年第6期546-548,共3页 Journal of Apoplexy and Nervous Diseases
基金 国家自然科学基金联合基金资助项目(No.U1503222)
关键词 中性粒细胞/淋巴细胞比值 帕金森病 周围神经病 神经肌电图 Neutrophil/Lymphocyte Ratio Parkinson's disease Peripheral neuropathy Neuroelectromyography
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