摘要
胰岛素样生长因子(IGFs)属于类胰岛素的多肽类生长因子,通过与细胞膜酪氨酸受体结合,调控细胞的增殖、分化、凋亡,以及机体的生长发育,参与疾病及肿瘤的发生发展。近年来IGFs家族在皮肤病方面的研究日益增多,本文总结了IGFs与皮肤病的相关进展。
Insulin-like growth factors(IGFs)are polypeptides structurally homologous to insulin.By binding to membrane tyrosine receptors,they regulate the proliferation,differentiation, apoptosis,growth,and development of body cells and are involved in the pathogenesis of tumors and other diseases.In recent years,more research on IGFs of dermatosis increased.This article reviews recent research advances in IGFs and its relationship with dermatosis.
作者
汤红燕
肖斌
王利平
杨桂兰
TANG Hongyan;XIAO Bin;WANG Liping;YANG Guilan(Department of Dermatology,the Second Affiliated Hospital of Lanzhou University,Lanzhou 730000,China)
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2019年第3期415-418,共4页
Acta Academiae Medicinae Sinicae
基金
教育部重点实验室开放课题基金(HS2017-1-003)~~
