摘要
目的探讨产后出血患者临床应用卡前列素氨丁三醇、米索前列醇以及缩宫素联合治疗的效果。方法 92例产后出血患者,根据治疗方法不同分为对照组和观察组,各46例。对照组实施常规治疗,观察组应用卡前列素氨丁三醇、米索前列醇以及缩宫素联合治疗。对比两组患者治疗前后血流动力学水平及治疗效果、产后24 h出血量、产后持续出血时间。结果观察组患者的治疗总有效率为97.83%,高于对照组的86.96%,差异具有统计学意义(P<0.05)。治疗前,两组患者的心率、舒张压、收缩压水平对比,差异均无统计学意义(P<0.05);治疗后,两组患者的心率、舒张压、收缩压水平均优于治疗前,且观察组患者的心率、舒张压、收缩压水平均优于对照组,差异均具有统计学意义(P<0.05)。观察组的产后24 h出血量及产后持续出血时间分别为(568.72±7.25)ml、(25.35±1.05)h,均优于对照组的(740.52±6.52)ml、(31.78±3.26)h,差异具有统计学意义(P<0.05)。结论产后出血患者应用卡前列素氨丁三醇、米索前列醇与缩宫素联合应用临床价值高,即可调整患者血流动力学,还可减少患者机体出血时间,保证生命安全,提升治疗效率。
Objective To discuss the effect of combined application of carboprost tromethamine, misoprostol and oxytocin in postpartum hemorrhage. Methods A total of 92 postpartum hemorrhage patients were divided by different treatment methods into control group and observation group, with 46 cases in each group. The control group received conventional therapy, and observation group received combined application of carboprost tromethamine, misoprostol and oxytocin. Comparison were made on hemodynamics before and after treatment and treatment effects, 24 h postpartum hemorrhage, postpartum continuous hemorrhage time between the two groups. Results The observation group had higher total treatment effective rate as 97.83% than 86.96% in the control group, and the difference was statistically significant (P<0.05). Before treatment, both groups had no statistically significant difference in heart rate, diastolic blood pressure, systolic blood pressure level (P<0.05). After treatment, both groups had better heart rate, diastolic blood pressure, systolic blood pressure than those before treatment, and the observation group had better heart rate, diastolic blood pressure, systolic blood pressure than the control group. Their difference was statistically significant (P<0.05). The observation group had better 24 h postpartum hemorrhage and postpartum hemorrhage time respectively as (568.72 ± 7.25) ml and (25.35 ± 1.05) h than (740.52 ± 6.52) ml and (31.78 ± 3.26) h in the control group. Their difference was statistically significant (P<0.05). Conclusion Combined application of carboprost tromethamine, misoprostol and oxytocin shows high clinical value for patients with postpartum hemorrhage. It can adjust the hemodynamics of patients, reduce bleeding time, ensure the safety of life and improve treatment efficiency.
作者
岳俊云
YUE Jun-yun(Department of Obstetrics and Gynecology, Shandong Liaocheng Dongchangfu People's Hospital, Liaocheng 252000, China)
出处
《中国实用医药》
2019年第16期19-21,共3页
China Practical Medicine
