摘要
目的探讨联合应用缩宫素、米索前列醇及卡前列素氨丁三醇预防性治疗产后出血的临床效果。方法选取2017年1月至2018年3月本院收治的剖宫产术中因子宫收缩乏力有产后出血倾向的患者62例为研究对象,根据随机数字表法分为观察组与对照组,每组31例。对照组患者使用缩宫素、米索前列醇预防性治疗,观察组患者给予缩宫素、米索前列醇以及卡前列素氨丁三醇预防性治疗,两组患者均用药治疗1次。评估比较两组患者的临床疗效;比较两组患者术中、术后2 h、术后24 h出血量,持续出血时间及住院时间;比较两组患者的不良反应发生情况。结果观察组患者产后出血的治疗总有效率(93. 55%)显著高于对照组(74. 20%),临床治疗效果显著优于对照组,差异有统计学意义(P <0. 05)。观察组患者术中、术后2 h、术后24 h出血量均显著少于对照组,持续出血时间、住院时间显著短于对照组,差异有统计学意义(P <0. 05)。两组患者的不良反应发生率比较差异无统计学意义(P> 0. 05)。结论联合使用缩宫素、米索前列醇以及卡前列素氨丁三醇预防性治疗产后出血临床效果显著,可有效减少产妇术后出血量,缩短产妇的持续出血时间及住院时间,值得推广应用。
Objective To explore the clinical effect of oxytocin and misoprostol combined with carboprost tromethamine in the prevention and treatment of postpartum hemorrhage. Methods A total of 62 cases with postpartum hemorrhage tendency due to uterine inertia during cesarean section admitted to our hospital from January 2017 to March 2018 were selected as study objects and randomly divided into observation group and control group, with 31 cases in each group. The control group was treated with oxytocin and misoprostol, the observation group was treated with oxytocin and misoprostol combined with carboprost tromethamine. The two groups of patients were treated with medication once. The clinical effects between the two groups were compared. The amount of intraoperative, 2h postoperative, 24h postoperative bleeding volume, continuous bleeding time and length of stay and occurrence of adverse reactions between the two groups were compared. Results The total effective rate of the observation group (93.55%) was significantly higher than that of the control group (74.20%), clinical effect is significantly better than the control group, the difference was statistically significant ( P <0.05 ). The amount of intraoperative , 2h postoperative, 24h postoperative bleeding volume in the observation group were significantly less than those in the control group, the continuous bleeding time and length of stay were significantly shorter than those in the control group, the difference was statistically significant ( P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups ( P >0.05). Conclusion Oxytocin and misoprostol combined with carboprost tromethamine in treating postpartum hemorrhage is remarkable in curative effect, can effectively reduce the amount of bleeding and shorten the continuous bleeding time and length of stay, which is worthy of clinical application.
作者
黄益辉
李萍
曾玲
HUANG Yihui;LI Ping;ZENG Ling(Department of Obstetrics,Huidong People′s Hospital,Huizhou 516300,China;Department of Obstetrics andGynecology,Huidong Second People′s Hospital,Huizhou 516300,China)
出处
《内科》
2019年第2期174-176,共3页
Internal Medicine
