摘要
目的评价布托啡诺复合丙泊酚滴定给药在日间胃肠镜手术患者中的应用效果.方法选取2017年11月~2018年9月我院自愿接受日间胃肠镜手术的60例患者作为研究对象,随机分为对照组和观察组,每组各30例.对照组采取丙泊酚麻醉,观察组在对照组的基础上使用布托啡诺,比较两组患者术前、术中及术后的血氧饱和度(SpO2)、心率(HR)、平均动脉压(MAP)、麻醉后意识消失时间、苏醒时间、丙泊酚的使用剂量、麻醉效果以及呼吸抑制发生率.结果术中两组患者的SpO2、HR和MAP均有所下降,观察组的SpO2、HR和MAP高于对照组(P<0.05);观察组患者的麻醉起效时间、苏醒时间短于对照组(P<0.05);观察组患者丙泊酚的使用剂量少于对照组(P<0.05);观察组的麻醉有效率高于对照组(P<0.05);观察组的呼吸抑制发生率低于对照组(P<0.05).结论布托啡诺复合丙泊酚滴定给药应用于日间胃肠镜手术,镇痛效果确切,可明显减少丙泊酚的用量,不良反应发生率较低,是一种较为理想的麻醉方法,值得在医院推广应用.
Objective To evaluate the application effect of Butorphanol combined with Propofol in daytime gastrointestinal endoscopic surgery. Methods Sixty patients who underwent voluntary gastrointestinal endoscopic surgery from November 2017 to September 2018 in our hospital were selected as the subjects, and randomly divided into control group (30 cases) and observation group (30 cases). The control group was anesthetized with Propofol, and the observation group was treated with Butorphanol on the basis of the control group. The differences of blood oxygen saturation (SpO2), heart rate (HR), mean arterial pressure (MAP), consciousness disappearance time after anesthesia, recovery time, dose of Propofol, anesthetic effect and adverse reactions before, during and after operation were compared between the two groups. Results The SpO2, HR and MAP of the two groups were decreased during the operation, and the SpO2, HR and MAP in the observation group were significantly higher than those in the control group (P<0.05). The anesthesia onset time and recovery time of the observation group were shorter than those of the control group (P<0.05). The dose of Propofol in the observation group was less than thtil in the control group (P<0.05). The anesthetic effect rate of the observation group was higher than that of the control group (P<0.05). The incidence of respiratory depression of the observation group was lower than that of the control group (P<0.05). Conclusion The analgesic effect of Butorphanol combined with Propofol titration in daytime gastrointestinal endoscopic surgery is obvious, and the amount of Propofol can be significantly reduced, and the incidence of adverse reactions is low. It is an ideal anesthesia method and it is worthy of promotion and application in hospitals.
作者
冯建标
陈伟元
汪福群
杨春艳
叶阮昊
FENG Jian-biao;CHEN Wei-yuan;WANG Fu-qun;YANG Chun-yan;YE Ruan-hao(Department of Anesthesiology, Meizhou People's Hospital, Guangdong Province, Meizhou 514000, China)
出处
《中国当代医药》
2019年第15期120-122,共3页
China Modern Medicine
关键词
日间胃肠镜手术
丙泊酚
布托啡诺
血氧饱和度
心率
麻醉效果
Daytime gastrointestinal endoscopic surgery
Propofol
Butorphanol
Blood oxygen saturation
Heart rate
Anesthetic effect
