摘要
目的:研究踝臂指数对腹膜透析患者心血管事件的预测价值。方法:本次研究于医院内部选取2014年11月-2015年11月收治的160例慢性肾脏病腹膜透析患者作为研究对象,对两组患者的生命体征及生化检验指标进行检测,根据踝臂指数计算结果对患者进行临床分组,将其分为高指数组与对照组,对比两组患者的心血管疾病发生情况和血清标志物指标水平,并分析患者心血管风险因素与高踝臂指数的关系。结果:高指数组的心血管疾病患病率为42.50%,显著高于对照组的25.00%(P<0.05);高指数组的血钙、血磷、甲状旁腺激素和超敏C-反应蛋白的平均水平分别为(2.37±0.17)mmol/L、(2.79±0.14)mmol/L、(186.84±54.64)pg/mL和(10.68±5.67)mg/L,均显著高于对照组的(2.26±0.22)mmol/L、(2.04±0.36)mmol/L、(102.34±32.85)pg/mL和(8.75±3.95)mg/L,(P<0.05);高指数组的血清总胆固醇、肿瘤坏死因子-α和铁调素指标水平分别为(6.12±0.85)mmol/L、(37.79±10.14)pg/mL、(47.84±1.64)ng/mL,均显著高于对照组的(3.45±0.49)mmol/L、(25.85±4.36)pg/mL、(40.34±5.85)ng/mL,(P<0.05)。结论:不同踝臂指数的腹膜透析患者,在心血管疾病发病率、血清标志物指标水平上,均具有明显的差异,根据患者的踝臂指数能够对其心血管疾病的发生和发展进行科学的预测,为心血管疾病的检查和预防提供更加丰富的指标基础。
Objective:To study the predictive value of ankle brachial index (CBI) for cardiovascular events in peritoneal dialysis patients.Methods:In this study,160 patients with chronic renal diseases treated in our hospital from November 2014 to November 2015 were selected as the research subjects.The vital signs and biochemical test indexes of the two groups were detected,and the patients were divided into high finger array group and the control group according to the results of ankle brachial index calculation.The incidence of cardiovascular disease and serum markers were compared between the two groups,and the relationship between the cardiovascular risk factors and the high ankle brachial index was analyzed.Results:The incidence of cardiovascular disease in the high finger array group was 42.50%,which was significantly higher than that of the control group,25%(P < 0.05);the average levels of blood calcium,phosphorus, parathyroid hormone and hypersensitive C reactive protein in the high finger array group was (2.37±0.17) mmol/L,(2.79±0.14) mmol/L,(186.84±54.64) pg/mL and (10.68±5.67) Mg/L respectively,which was significantly higher than that of the control group,(2.26±0.22) mmol/L,(2.04±0.36) mmol/L,(102.34±32.85) pg/mL and (8.75±3.95) mg/L respectively (P < 0.05),and the level of serum total cholesterol,tumor necrosis factor - alpha and fertin index of the high finger array group was (6.12±0.85) mmol/L,(37.79±10.14) pg/ mL,(47.84±1.64) ng/mL respectively,which was significantly higher than that in the control group,(3.45±0.49) mmol/L,(25.85±4.36) pg/mL,(40.34±5.85) ng/mL respectively,(P < 0.05).Conclusion:The patients with different ankle brachial indices have significant differences in the incidence of cardiovascular disease and the level of serum markers.According to the ankle brachial index,the patients can scientifically predict the occurrence and development of cardiovascular diseases and provide more abundant reference for the examination and prevention of cardiovascular diseases.
作者
高中山
贾志斌
曾祥高
Gao Zhongshan;Jia Zhibin;Zeng Xianggao
出处
《中医临床研究》
2019年第12期28-30,共3页
Clinical Journal Of Chinese Medicine
基金
东莞市社会科技发展项目编号:201850715046787项目名称:踝臂指数对腹膜透析患者心血管事件的预测价值
关键词
踝臂指数
腹膜透析
慢性肾脏病
心血管事件
预测价值
Ankle brachial index
Peritoneal dialysis
Chronic kidney disease
Cardiovascular events
Predictive value
