摘要
目的探讨透析患者动静脉内瘘血栓形成长度与尿激酶溶栓治疗疗效的相关性。方法对2015年1月至2016年12月在重庆医科大学附属第二医院肾内科动静脉内瘘出现血栓形成并在36h内采用了尿激酶溶栓的50例患者,根据溶栓治疗效果分为溶栓成功组和溶栓失败组,分析两组患者内瘘血栓形成的长度与溶栓治疗效果的关系。结果溶栓成功38例,失败12例。血栓形成的长度与尿激酶溶栓治疗效果密切相关(β=-1.916,P=0.015)。结论血栓形成的长度作为溶栓治疗参考指标之一,为临床判断提供依据,提高溶栓治疗的有效率,保护内瘘血管免受不必要的损伤。
Objective To investigate the correlation between the length of arteriovenous fistula thrombosis and the efficacy of urokinase thrombolytic therapy in dialysis patients. Methods Fifty patients appearing thrombosis in the arteriovenous fistula treated by adopting urokinase thrombolytic therapy within 36 h in the nephrology department of the Second Affiliated Hospital of Chongqing Medical University from January 2015 to December 2016 were divided into the thrombolysis success group and thrombolysis failure group according to the effect of thrombolytic therapy.Then the relationship between the length of sputum thrombosis and the effect of thrombolytic therapy was analyzed. Results Thirty-eight cases successes in the thrombolysis therapy and 12 cases failed.The length of thrombosis (β=-1.916, P =0.015) was closely correlated to the efficacy of urokinase thrombolytic therapy. Conclusion The length of thrombosis serves as one of reference indicators for the thrombolytic therapy,provides the basis for clinical judgment,increases the effective rate of thrombolytic therapy and protects the fistula vessel from unnecessary injury.
作者
张英
罗艳佳
ZHANG Ying;LUO Yanjia(Department of Nephrology,Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)
出处
《重庆医学》
CAS
2019年第11期1895-1896,1901,共3页
Chongqing medicine
关键词
尿激酶
血栓形成长度
动静脉内瘘
溶栓
urokinase
length of thrombosis
arteriovenous fistula
thrombolysis
