摘要
目的分析儿童卵巢颗粒细胞瘤的CT特征及临床表现。方法回顾性分析经病理证实的12例女性卵巢颗粒细胞瘤患儿的术前CT和相关临床表现,观察卵巢肿物的性质、大小、钙化、强化程度、有无瘤内血管、子宫大小、盆腔积液及增大淋巴结等影像学特征。结果12例卵巢颗粒细胞瘤患儿以腹痛、性早熟或男性化等相关症状就诊;9例术前血清雌二醇水平升高,2例血清睾酮水平升高。CT平扫表现为实性肿物2例、囊实性8例、囊性肿物2例,长径中位数为82.50(46.75,111.00)mm;肿瘤内钙化1例;盆腔内大量积液2例,子宫增大9例。增强扫描肿物实性成分明显强化,9例内见纡曲血管影,囊性肿物均无明显强化;未见淋巴结明显增大。结论结合特异性内分泌症状及相关激素水平、肿瘤标记物改变,CT发现儿童血供丰富的卵巢肿物、伴子宫体积增大高度提示卵巢颗粒细胞瘤。
Objective To analyze CT manifestations and clinical features of pediatric ovarian granulosa cell tumor(GCT)in children. Methods Preoperative CT images and clinical data of 12 girls with ovarian GCT were retrospectively analyzed. CT manifestations of ovarian GCT, including the quality and size of tumor, calcification, enhancement degree, vessels in tumor, size of uterine, pelvic effusion and lymphadenovarix were observed. Results The chief complaints included abdominal pain, precocious puberty or virilization. Preoperative serum estradiol level increased in 9 patients and serum testosterone level increased in 2 patients. Solid tumor(n=2), cystic-solid(n=8) and cystic mass(n=2) were showed in plain CT images, with the median diameter of 82.50(46.75, 111.00)mm. Calcifications(n=1) and massive pelvic effusion(n=2) were rare, whereas hysterauxesis was common(n=9). After administration of contrast media, the solid components of tumors enhanced obviously, and vessels in tumors were seen in 9 cases. The cystic mass did not obviously enhance. No obvious enlarged lymph node was found in all patients. Conclusion Ovarian neoplasm with hysterauxesis and rich vascular supply showed on CT highly suggest ovarian granulosa cell tumor in children combined with specific endocrine symptoms and changes in hormone levels and tumor markers.
作者
陶然
杨梅
袁新宇
杨洋
郭红伟
刘海霞
TAO Ran;YANG Mei;YUAN Xinyu;YANG Yang;GUO Hongwei;LIU Haixia(Department of Radiology, Affiliated Children's Hospital, Capital Institute of Pediatrics, Beijing 100020, China)
出处
《中国医学影像技术》
CSCD
北大核心
2019年第6期882-885,共4页
Chinese Journal of Medical Imaging Technology
