摘要
【目的】分析改良HoLEP术式与TURP术式治疗良性前列腺增生的疗效及安全性。【方法】回顾性分析2018年1~12月本院收治的236例BPH患者的临床资料,根据治疗方法的不同将其分为HoLEP组(n=143)和TURP组(n=93)。分析二组患者术前及术后3个月最大尿流率(Qmax)、膀胱残余尿量(RUV)、膀胱过度活动症状评分(OABSS)、国际前列腺症状评分(IPSS)和生活质量评分(QOL),并记录围术期相关指标以及术后并发症。【结果】HoLEP组患者手术时间以及切除组织重量显著高于TURP组,而在术中出血量、尿管留置时间以及住院时间方面显著低于TURP组,差异有统计学意义(P<0.05);随访3个月后发现,TURP组患者并发症发生率为27.96%显著高于HoLEP组患者的10.49%,差异具有统计学意义(P<0.05);两组患者Qmax、RUV、OABSS、IPSS和QOL较术前均显著改善(P<0.05),但组间比较差异无统计学意义(P>0.05)。【结论】HoLEP 与 TURP 治疗前列腺良性增生临床疗效相当,但HoLEP对患者损伤小,安全性更高,且患者术后恢复较快。
【Objective】To analyze the efficacy and safety of modified HoLEP and TURP in the treatment of benign prostatic hyperplasia.【Methods】A retrospective analysis of 236 patients with benign prostatic hyperplasia who were admitted to our hospital from January to December 2018 and divided into two groups according to the treatment plan. Among them, 143 patients underwent holmium laser prostate removal (HoLEP), while the remaining 93 patients underwent conventional transurethral resection of the prostate (TURP). The maximum urinary flow rate (Qmax), residual bladder volume (RUV), overactive bladder symptom score (OABSS), international prostate symptom score (IPSS), and quality of life score (QOL) were analyzed before and 3 months after surgery. Perioperative related indicators and postoperative complications were recorded.【Results】The operation time and the weight of resected tissue in the HoLEP group were significantly higher than those in the TURP group, however, the intraoperative blood loss, urinary catheter indwelling time and hospitalization time were significantly lower than those in the TURP group (P<0.05). After 3 months, 27.96% of patients in the TURP group had complications, and 10.49% of patients in the HoLEP group had complications;the difference was statistically significant (P<0.05). Compared to those before surgery, the Qmax, RUV, OABSS, IPSS and QOL of the two groups were improved after surgery(P<0.05). However, the differences between the groups were not statistically significant (P>0.05).【Conclusion】HoLEP and TURP are equivalent to the clinical efficacy of benign prostatic hyperplasia. HoLEP has less damage, more safety and faster recovery after surgery.
作者
夏宗禹
王琴
刘胜
XIA Zong-yu;WANG Qin;LIU Sheng(Department of Urology, Chongqing Three Gorges Central Hospital, Chongqing 404000, China)
出处
《医学临床研究》
CAS
2019年第5期894-896,共3页
Journal of Clinical Research
