摘要
目的研究改良前列腺钬激光剜除术(HoLEP)术式与前列腺电切术(TURP)术式对良性前列腺增生患者术后性功能和生活质量的影响。方法选择2015年1月至2017年1月在本院接受治疗的良性前列腺增生患者124例,根据治疗方案不同分为观察组和对照组,对照组给予TURP术治疗,观察组给予改良HoLEP术式治疗。比较两组手术时间、术中出血量、尿管留置时间、术后膀胱冲洗时间及住院时间。于术毕、术后3、6、9、12个月观察两组最大尿流率、剩余尿液水平及国际前列腺症状评分(IPSS)、生活质量指数评分(QOL)、国际勃起功能评分表(IIEF-5)评分;术后6个月,观察两组勃起功能障碍及逆行射精发生率,并比较其并发症发生率。结果观察组术中出血量、尿管留置时间、术后膀胱冲洗时间及住院时间均明显低于对照组,比较差异有统计学意义(P<0.05);两组手术时间比较差异无统计学意义(P>0.05);术后不同时间点,两组患者最大尿流率呈上升趋势,观察组上升幅度高于对照组(P<0.05);两组患者剩余尿液水平呈下降趋势,观察组下降程度显著低于对照组(P<0.05);术后不同时刻IPSS与QOL评分均低于对照组,比较差异有统计学意义(P<0.05);两组勃起功能障碍及逆行射精发生率比较差异无统计学意义(P>0.05);观察组术后并发症发生率明显低于对照组,比较差异有统计学意义(P<0.05)。结论改良HoLEP术式相比TURP术式治疗良性前列腺增生,其疗效显著,可显著提高患者生活质量,降低术后并发症,且不会增加对术后性功能的影响。
Objective To study affect of improve holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostatic (TURP) on sexual function and living quality of patients with benign prostatic hyperplasia. Methods From January 2015 to January 2017, 124 patients with benign prostatic hyperplasia who received therapy in our hospital were selected as research objects, were divided into observation group and control group according to different methods, control group was given treatment of TURP, observation group was given improved HoLEP surgical treatment. The operation time, intraoperative blood volume, urinary catheter time, postoperative bladder irrigation time and hospital stay time of two groups were compared. The maximal urine flow rate, residual urine level and international prostate symptom score (IPSS), quality of life (QOL) and international index of erectile function 5 (IIEF-5) scores of the two groups were observed after surgery and at 3, 6, 9 and 12 months after operation, the incidence of erectile dysfunction and retrograde ejaculation was observed and the incidence of complications was compared 6-months after operation. Results The intraoper-ative blood volume, urinary catheter time, postoperative bladder irrigation time and hospitalization time were significantly lower than those in the control group(P<0.05). The operation time was no significant difference between the two groups (P>0.05), and the maximum urine flow rate of the two groups showed an upward trend at different time points after operation, the maximum urine flow rate in the two groups was higher than that in the control group (P<0.05). The residual urine levels in the two groups were decreased, the decrease of the observation group was significantly lower than that of the control group (P<0.05), and the scores of IPSS and QOL were lower than those in the control group at the post operation time, and the difference was significant (P<0.05). There was no significant difference between two groups of erectile dysfunction an
作者
黄鹏
Huang Peng(Department of Urology,Yangling Demonstration Area Hospital,Xianyang 712100,China)
出处
《国际泌尿系统杂志》
2019年第1期84-87,共4页
International Journal of Urology and Nephrology
关键词
前列腺增生
经尿道前列腺切除术
生活质量
Prostatic Hyperplasia
Transurethral Resection of Prostate
Quality of Life
