摘要
目的探究对社区获得性肺炎伴发热患者实施哌拉西林钠他唑巴坦钠注射剂联合地塞米松注射液治疗的效果。方法随机将2017年1月-2018年9月方便选取的该院60例社区获得性肺炎伴发热患者分为观察组(30例,应用哌拉西林钠他唑巴坦钠注射剂联合地塞米松注射液治疗)、对照组(30例,应用哌拉西林钠他唑巴坦钠注射剂治疗)。对比两组患者的疗效、血常规恢复正常时间、住院时间、炎症因子水平及不良反应发生率。结果观察组患者总有效率(96.67%)高于对照组(80.00%)(χ^2=4.043,P<0.05);观察组患者血常规恢复正常时间、住院时间均少于对照组(t=11.800、3.773,P<0.05);观察组患者治疗后IL-6、IL-10、TNF-α水平均低于对照组(t=19.117、11.090、42.617,P<0.05);观察组患者不良反应发生率(13.33%)和对照组(10.00%)差异无统计学意义(χ^2=0.162,P>0.05)。结论对社区获得性肺炎伴发热患者实施哌拉西林钠他唑巴坦钠注射剂联合地塞米松注射液治疗可加速症状缓解,减轻炎症反应,缩短住院时间,效果较佳,且安全性较好。
Objective To investigate the effect of piperacillin sodium tazobactam sodium injection combined with dexamethasone injection in community-acquired pneumonia with fever. Methods January 2017 to September 2018, Convenient select a total of 60 patients with community-acquired pneumonia with fever admitted to our hospital were randomly divided into observation group(30 cases, treated with piperacillin sodium tazobactam sodium injection combined with dexamethasone injection), and control group(30 cases, treated with piperacillin sodium tazobactam sodium injection). The efficacy,blood routine recovery time, hospitalization time, inflammatory factor level and adverse reaction rate were compared. Results The total effective rate of the observation group was 96.67%, which was higher than that of the control group(80.00%),(χ^2=0.043, P<0.05). The blood routine recovery time and hospitalization time of the observation group were less than those of the control group(t=11.800, 3.773, P<0.05). The levels of IL-6, IL-10 and TNF-α in the observation group were lower than those in the control group(t=19.117, 11.090, 42.617, P<0.05). The incidence of adverse reactions in the observation group was 13.33%, and 10.00% in the control group. There was no significant difference between the two groups(χ^2=0.162, P>0.05). Conclusion The administration of piperacillin sodium tazobactam sodium injection combined with dexamethasone injection in community-acquired pneumonia with fever can accelerate symptom relief, reduce inflammation,shorten hospitalization time. And it safer and more effective.
作者
李硕
LI Shuo(Department of Emergency Pharmacy,Municipal Hospital,Heze,Shandong Province,274000 China)
出处
《中外医疗》
2019年第12期5-7,共3页
China & Foreign Medical Treatment
关键词
社区获得性肺炎
发热
哌拉西林钠他唑巴坦钠
地塞米松
炎症因子
不良反应
Community acquired pneumonia
Fever
Piperacillin sodium tazobactam sodium
Dexamethasone
Inflammatory factors
Adverse reactions
