摘要
目的评估Neuroform EZ支架置入治疗老年大脑中动脉(MCA)狭窄患者的疗效及安全性。方法纳入2017年2月~2018年11月解放军总医院神经内科介入中心住院治疗的伴有临床症状的MCA M1段重度狭窄患者52例,男性36例,女性16例,平均年龄为(63.00±1.25)岁,全部行脑数字减影血管造影(DSA)检查,明确存在MCA重度狭窄(70%~99%),并择期造影全麻下行Neuroform EZ支架置入治疗,术后21个月内不同时间段通过CT血管成像,DSA检查,以及电话随访,观察术后并发症情况,回顾性分析患者相关资料。结果52例患者手术均成功,共置入支架53枚,手术成功率100%。术后临床症状好转29例,占55.8%。术后出现病情恶化或新添临床表现等并发症患者3例,占5.8%,其中术后第3天出现支架内血栓形成,造成支架内闭塞1例;术后48h出现高灌注出血1例;术后出现患侧再发小穿支脑梗死事件1例。完成随访43例,随访率82.7%。结论用Neuroform EZ支架介入治疗老年MCA重度狭窄患者的疗效满意及安全性可靠。
Objective To assess the efficacy and safety of Neuroform EZ stent in the treatment of in elderly patients with middle cerebral artery(MCA)stenosis.Methods Fifty-two elderly patients(36 males and 16 females)aged 63.00±1.25 years with symptomatic severe MCA M1 stenosis admitted to our hospital from February 2017 to December 2018 were included in this study.Cerebral angiography(DSA)examination showed MCA severe stenosis(70%-99%).The patients were placed Neuroform EZ stent under local anesthesia and were follow-up for 21 months after operation through TCD,CTA,DSA to determine if there were postoperative complications.Their clinical data were retrospectively analyzed.Results Fifty-three Neuroform EZ stents were implanted in the 52 patients with a success rate of 100%.The clinical symptoms were improved in29 patients(55.8%)and the clinical symptoms became severer or new complications occurred in 3 patients(5.8%),including early instent thrombosis in 1 patient,instent occlusion in 1 patient,high perfusion hemorrhage in 1 patient at 48 hafter stenting,and lateral perforation in 1 patient.Forty-three(82.7%)out of the 52 patients were followed up.Conclusion Neuroform EZ is effective and satisfactory in the treatment of senile MCA severe stenosis,and the effect and safety of interventional therapy are reliable.
作者
王登宇
王君
张荣举
刘金敬
Wang Dengyu;Wang Jun;Zhang Rongju;Liu Jinjing(Department of Neurology,Chinese PLA General Hospital No.1 Medical Center,Beijing 100853,China)
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2019年第6期564-567,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
支架
大脑中动脉
颅内动脉疾病
脑梗死
脑缺血发作
短暂性
血管造影术
数字减影
stents
middle cerebral artery
intracranial arterial diseases
brain infarction
ischemic attack,transient
angiography,digital subtraction
