摘要
目的探讨微创穿刺术治疗大量自发性脑出血的临床效果。方法回顾性分析在我院诊治的79例大量自发性脑出血患者的临床资料。根据治疗方式将患者分为对照组(39例,行开颅手术治疗)和观察组(40例,行微创穿刺术治疗)。对比两组的治疗效果。结果治疗后2个月,两组的NIHSS评分显著降低,且观察组低于对照组(P<0.05)。治疗后24、36 h,观察组的S100B、GFAP及β神经生长因子水平均明显优于对照组(P<0.05)。治疗后1、2个月,两组的Fugl-Meyer运动功能评分均明显高于治疗前,且观察组高于对照组(P<0.05)。结论微创穿刺手术可有效治疗大量自发性脑出血,并且患者预后较好,值得临床推广和广泛应用。
Objective To investigate the clinical effect of minimally invasive puncture in the treatment of massive spontaneous cerebral hemorrhage. Methods The clinical data of 79 patients with massive spontaneous cerebral hemorrhage were retrospectively analyzed. According to the treatment method, the patients were divided into control group(39 cases,treated by craniotomy) and observation group(40 cases, treated by minimally invasive puncture). The therapeutic effects of the two groups were compared. Results At two months after treatment, the NIHSS scores of the two groups decreased significantly, and that of the observation group was lower than the control group(P <0.05). At 24 and 36 hours after treatment, the levels of S100 B, GFAP and β-nerve growth factor in the observation group were significantly better than those in the control group(P<0.05). At 1 and 2 months after treatment, the Fugl-Meyer motor function scores of the two groups were significantly higher than those before treatment, and those of the observation group were higher than the control group(P <0.05). Conclusion Minimally invasive puncture in the treatment of massive spontaneous intracerebral hemorrhage is effective, and the prognosis of patients is good. It is worthy of clinical promotion and wide application.
作者
李军
陈冬
LI Jun;CHEN Dong(the People's Hospital of Sanyuan County, Xianyang 713800, China)
出处
《临床医学研究与实践》
2019年第17期73-74,共2页
Clinical Research and Practice
关键词
大量自发性脑出血
微创穿刺术
开颅手术
神经功能
massive spontaneous intracerebral hemorrhage
minimally invasive puncture
craniotomy
neural function