摘要
目的:探讨何氏养肾方对Ⅲ、Ⅳ期糖尿病肾病(DN)中医症候积分及生化指标的影响。方法:将60例中期DN患者随机分为A组和B组,各30例。A组在基础治疗上予贝那普利治疗,B组在A组治疗上联合何氏养肾方治疗。比较两组治疗对中医症候积分及生化指标的影响。结果:(1)两组中医证候积分均降低,且B组降低更为明显(P<0.05)。(2)B组总有效率(86.67%)高于A组(66.67%)(P<0.05);(3)两组24h尿蛋白定量(24h UP)、24h尿微量白蛋白(24h U-MA)、血肌酐(Scr)水平较治疗前下降,B组降低程度大于A组(P<0.05)。结论:何氏养肾方可改善中期糖尿病肾病中医症状及生化指标。
Objective:To investigate the effect of on TCM syndromes score and biochemical indexes of middle stage diabetic nephropathy(DN).Methods:60 patients with intermediate DN were randomly divided into group A and group B,with 30 patients each. Group A was treated with benazepril on the basis of treatment,Group B was treated with Heshiyangshen prescription on the basis of the group A. The effects of treatment on TCM syndromes and biochemical indexes were compared between the two groups. Results:(1)The scores of TCM syndromes were reduced in both groups,and the decrease was more obvious in group B(P <0.05).(2)Total efficiency of Group B(90.00%)was significantly higher than that of the group A(66.67%)(P<0.05).(3)The 24 h urinary protein(24 hUP),24 hour urinary microalbumin(24 h U-MA)and Scr were reduced in both groups compared with that before treatment,and the reduction degree in group B was higher than that in group A(P<0.05). Conclusion:Heshiyangshen prescription could be improved the TCM symptoms and biochemical indexes in patients with middle stage diabetic nephropathy.
作者
周静仪
简炼
林捷
何世东
ZHOU Jing-yi;JIAN Lian;LIN Jie;HE Shi-dong(Traditional Chinese Medical Hospital of Dongguan City,Dongguan 523000,China)
出处
《内蒙古中医药》
2019年第4期125-127,共3页
Inner Mongolia Journal of Traditional Chinese Medicine
基金
东莞市科技计划医疗卫生类科研项目(2016105101057)
关键词
何氏养肾方
中期糖尿病肾病
中医症候积分
生化指标
Heshiyangshen prescription
Middle stage diabetic nephropathy
TCM syndrome score
Biochemical index
