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胺碘酮与利多卡因治疗急性心肌梗死后室性心律失常的疗效比较研究 被引量:12

Comparative effectiveness research of amiodarone and lidocaine in treating ventricular arrhythmias after acute myocardial infarction
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摘要 目的比较胺碘酮与利多卡因治疗急性心肌梗死后室性心律失常的临床疗效。方法回顾性分析阿克苏市人民医院2012年3月—2018年5月收治的急性心肌梗死后室性心律失常患者58例,根据治疗方案不同分为A组和B组,各29例。A组患者采用利多卡因治疗,B组患者采用胺碘酮治疗。比较两组患者临床疗效及治疗后舒张压(DBP)、收缩压(SBP),并观察两组患者不良反应发生情况。结果 B组患者临床疗效优于A组(P<0.05)。B组患者DBP、SBP及不良反应发生率低于A组(P<0.05)。结论胺碘酮治疗急性心肌梗死后室性心律失常的临床疗效优于利多卡因,其可更有效改善患者的临床症状及体征,且降压效果明显,安全性更高。 Objective To compare the clinical effect of amiodarone and lidocaine in treating ventricular arrhythmias after acute myocardial infarction.Methods A total of 58 cases of patients with ventricular arrhythmias after acute myocardial infarction were selected from March 2012 to May 2018 in Aksu People's Hospital,which were divided into A group and B group according to different methods,29 cases in each group.The A group was treated with lidocaine,B group was treated with amiodarone.The clinical effect and DBP,SBP were compared between the two groups,and the incidence of adverse reactions were observed.Results The clinical effect of B group was better than A group(P<0.05).The B group of DBP,SBP and incidence rate of adverse reactions were lower than A group(P<0.05).Conclusion Amiodarone has a better clinical effect for ventricular arrhythmias after acute myocardial infarction than lidocaine,it can effectively improve the clinical symptoms and signs of patients,and with high safety.
作者 马乐平 金茹 MA Le-ping;JIN Ru(Aksu People's Hospital, Aksu 843000, China)
出处 《临床合理用药杂志》 2019年第12期6-7,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 心律失常 心性 急性心肌梗死 胺碘酮 利多卡因 疗效比较研究 Arrhythmias,cardiac Acute myocardial infarction Amiodarone Lidocaine Comparative effectiveness research
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