摘要
目的观察四妙散联合非布司他对痛风性关节炎患者的临床效果影响。方法选取自2016年10月至2017年10月于大连市友谊医院中医科住院治疗的痛风性关节炎患者60例,所有研究对象通过信封法随机分组,对照组30例,应用非布司他治疗干预方式,试验组30例,应用四妙散联合非布司他治疗干预方式,观察两组患者治疗前后血尿酸、C反应蛋白及临床有效率变化情况。结果治疗后:①对照组UA(421.96±42.38)μmg/L,试验组(317.67±32.71)μmg/L;②对照组CRP(19.42±4.34)mg/L,试验组(7.65±2.11)mg/L;③对照组有效率86.67%,试验组96.67%,两组数据比较差异具有统计学意义(P<0.05)。结论四妙散联合非布司他治疗痛风性关节炎患者可有效加速尿酸代谢速度,恢复嘌呤代谢紊乱,控制机体周围组织炎性改变,祛风除湿、活血止痛,临床疗效优异,值得推广。
Objective To observe the clinical effect of Simiaosan combined with febuxostat on gouty arthritis patients.Methods Sixty patients with gouty arthritis who were hospitalized in Dalian Friendship Hospital from October 2016 to October 2017 were selected.All the subjects were randomly divided into groups.In the control group,30 cases were treated with febuxostat Treatment intervention,the experimental group of 30 cases,the application of Simiaosan combined with febuxostat treatment intervention,observed serum uric acid,C-reactive protein and clinical efficiency changes.Result①the control group UA(421.96±42.38)μmg/L,the experimental group(317.67±32.71)μmg/L;②the control group CRP(19.42±4.34)mg/L,the experimental group(7.65±2.11)mg/L;③control group Efficiency 86.67%,test group 96.67%,the difference was statistically significant(P<0.05).Conclusion The treatment of patients with gouty arthritis with Simiaosan combined with febuxostat can effectively accelerate the rate of uric acid metabolism,expelling wind,and is worthy of promotion.
作者
戚虹百
杨坤
金延萍
QI Hong-bai;YANG Kun;JIN Yan-ping(Department of Traditional Chinese Medicine, Dalian Friendship Hospital, Dalian 116001, China;Department of Gastroenterology, Dalian Second People's Hospital, Dalian 116011, China)
出处
《中国医药指南》
2019年第14期40-41,共2页
Guide of China Medicine
