摘要
目的探讨结节性硬化症在体共聚焦激光扫描显微镜(CLSM)的影像学特征。方法选取皮肤科7例结节性硬化症患者,经CLSM检查后进行组织病理确诊,分析其影像学特征。结果与周围正常皮肤相比,结节性硬化症在CLSM下可观察到毛囊周围的色素环围绕毛囊呈条状环形同心排列,伴基底层色素增多,真皮浅、中层及毛囊周围胶原折光较高,且毛囊周围胶原呈现网格状改变。结论结节性硬化症的CLSM图像有明显的特征性,且与其常规组织病理特征具有很好的一致性,可为该病的临床诊断和鉴别诊断提供有效的帮助。
Objective To explore the image features of tuberous sclerosis by confocal laser scanning microscope(CLSM).Methods Seven patients with tuberous sclerosis were selected from dermatology department and were detected by CLSM.At the same time,the image features of tuberous sclerosis were analyzed after the diagnosis of pathological tissues.Results Compared with the surrounding normal skin,the images of tuberous sclerosis in CLSM can be observed that the pigment ring around the hair follicle presented concentric arrangement,pigment in the base increased,collagen refractive index in the shallow and middle dermis and around the hair follicle was higher,which presented grid change around the hair follicles.Conclusion The images of tuberous sclerosis in CLSM have obvious characteristic and are consistency with histopathologic features.It can provide effective help for the clinical diagnosis and differential diagnosis of tuberous sclerosis.
作者
雷东春
张守民
李振鲁
王建波
李建国
袁星海
王豫平
王国芳
LEI Dongchun;ZHANG Shoumin;LI Zhenlu;WANG Jianbo;LI Jianguo;YUAN Xinghai;WANGYuping;WANG Guofang(Department of Dermatology, Henan Provincial People's Hospital, Zhengzhou 450003, China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2019年第6期657-660,共4页
The Chinese Journal of Dermatovenereology
