摘要
目的对比观察烧伤创疡再生医疗技术(moist exposed burn therapy/moist exposed burn ointment,MEBT/MEBO)治疗小儿会阴部烫伤的临床疗效。方法选取2008年3月至2017年12月德州市第二人民医院烧伤科收治的650例会阴部烫伤患儿作为研究对象,并按照随机数表法将其随机分为观察组(340例)与对照组(310例),其中观察组患儿采用MEBT/MEBO治疗局部创面,对照组患儿采用磺胺嘧啶银乳膏治疗局部创面,对比观察两组患儿会阴部烫伤创面的愈合时间及瘢痕增生情况。结果观察组患儿会阴部浅Ⅱ度创面愈合时间为(8.45±1.25)d、深Ⅱ度创面愈合时间为(21.79±1.58)d、浅Ⅲ度创面愈合时间为(34.23±2.64)d,均明显短于对照组患儿的会阴部浅Ⅱ度创面愈合时间(12.42±1.64)d、深Ⅱ度创面愈合时间(27.83±1.96)d、浅Ⅲ度创面愈合时间(41.18±2.94)d,两组对比,P均<0.01,差异具有统计学意义。观察组患儿深Ⅱ度创面愈后皮肤留有表浅性瘢痕者9例、留有增生性瘢痕者6例,浅Ⅲ度创面愈后皮肤留有增生性瘢痕者13例;对照组患儿深Ⅱ度创面愈后皮肤留有表浅性瘢痕者28例、留有增生性瘢痕者49例,浅Ⅲ度创面愈后皮肤留有增生性瘢痕者39例,两组患儿瘢痕增生情况对比,P<0.01,差异具有统计学意义。结论MEBT/MEBO治疗小儿会阴部烫伤创面,可在有效促进创面愈合,缩短创面愈合时间的同时,降低瘢痕增生率,疗效显著,临床应用价值较高。
Objective To observe the clinical efficacy of Moist Exposed Burn Therapy/Moist Exposed Burn Ointment(MEBT/MEBO)in the treatment of pediatric perineal scalds.Methods Six hundred and fifty children patients with perineal scalds admitted into the Burns Department of The Second People’s Hospital of Dezhou between March 2008 and December 2017 were selected as subjects to be divided into an observation group(340 patients)and a control group(310 patients)according to the random number table.In the observation group,the local wounds were treated with MEBT/MEBO while in the control group the local wounds were treated with SD-Ag Cream.The wound healing time and scar hyperplasia condition were observed and compared between the two groups.Results In the observation group,the healing time was(8.45±1.25)d for superficialⅡdegree wounds,(21.79±1.58)d for deepⅡdegree wounds and(34.23±2.64)d for superficialⅢdegree wounds,which were obviously shorter than the corresponding(12.42±1.64)d,(27.83±1.96)d and(41.18±2.94)d in the control group and the differences were statistically significant(all P<0.01).In the observation group,superficial scar in 9 cases and scar hyperplasia in 6 cases were found on the healed skin of deepⅡdegree wounds,and scar hyperplasia in 13 cases were found on the healed skin of superficialⅢdegree wounds,while in the control group superficial scar and scar hyperplasia were respectively seen on the healed skin of 28 cases and 49 cases with deepⅡdegree wounds,and scar hyperplasia was seen in 39 cases on the healed skin of superficialⅢdegree wounds.The comparison of scar hyperplasia condition between the two groups showed statistically significant difference,P<0.01.Conclusion In the treatment of pediatric perineal scalds,MEBT/MEBO can effectively promote wound healing,shorten wound healing time and decrease the occurrence of scar hyperplasia,presenting significant clinical efficacy and high clinical application value.
作者
赵法军
吕文杰
Zhao Fajun;Lv Wenjie(Burns Department,The Second People's Hospital of Dezhou,Dezhou City,Shandong 253000,China)
出处
《中国烧伤创疡杂志》
2019年第3期192-195,共4页
The Chinese Journal of Burns Wounds & Surface Ulcers
