摘要
目的探讨阴道镜联合基液细胞监测技术筛查宫颈癌前病变的价值。方法收集2018年1~8月来我院就诊且行宫颈/阴道细胞学筛查患者9261例,采集其标本,并对结果异常者行阴道镜检查及多点活检组织病理学检查。以宫颈病理学检查为标准,统计阴道镜联合基液细胞监测结果与病理检查结果的符合率。结果基液细胞学宫颈癌筛查标本9261例,正常范围内8883例(95.9%),异常涂片378例(4.1%);异常涂片378例中,非典型鳞状细胞(ASC)+非典型腺细胞(AGC)189例(50.0%),鳞状上皮细胞内低度病变(LSIL)119例(31.5%),鳞状上皮细胞内高度病变(HSIL)49例(13.0%),鳞状细胞癌(SCC)21例(5.5%)。阴道镜联合基液细胞阳性与病理学检查的总符合率为50.0%,其中ASC+AGC、LSIL、HSIL、SCC诊断符合率分别为29.6%、52.9%、85.7%、100.0%。阴道镜联合基液细胞监测下,ASC+AGC及LSIL与宫颈病理学检查的符合率比较,差异有统计学意义(χ^2=8.014,P<0.05);HSIL及SCC与宫颈病理学检查的符合率比较,差异无统计学意义(χ^2=0.875,P>0.05)。结论阴道镜联合基液细胞监测技术筛查宫颈癌前病变,方法可靠,与病理结果符合率高,可联合推广应用。
Objective To explore the value of colposcopy combined with basal fluid cell monitoring technique in screening cervical precancerous lesions. Methods A total of 9261 patients who underwent cervical/vaginal cytology screening in our hospital from January to August 2018 were enrolled. The specimens were collected and colposcopy and multi-point biopsy were performed on the abnormalities. According to the cervical pathological examination,the coincidence rate between the results of colposcopy combined with basal fluid cell monitoring and pathological examination was calculated. Results There were 9261 cases of cervical cancer screening specimens from basal fluid cytology,in which 8883 cases (95.9%) were in the normal range,and 378 cases (4.1%) were abnormal smears. Among 378 cases of abnormal smears,189 cases (50.0%) were atypical squamous cells (ASC)+atypical glandular cells (AGC),119 cases (31.5%) were low-grade lesions in squamous intraepithelial cells (LSIL),49 cases (13.0%) were high-grade lesion in squamous epithelial cells (HSIL),and 21 cases (5.5%) were squamous cell carcinoma (SCC). The total coincidence rate of colposcopy combined with basal cell positive and pathological examination was 50.0%,among which the diagnostic coincidence rate of ASC+AGC,LSIL,HSIL and SCC was 29.6%,52.9%,85.7% and 100.0%,respectively. Under the colposcopy combined with basal fluid cell monitoring,the coincidence rate of ASC+AGC and LSIL with cervical pathology was statistically significant (χ^2=8.014,P<0.05). There was no significant difference in the coincidence rate between HSIL and SCC and cervical pathology (χ^2=0.875,P>0.05). Conclusion Colposcopy combined with basal fluid cell monitoring technology is a reliable method in screening cervical precancerous lesions,and the coincidence rate with pathological results is high,which can be jointly promoted and applied.
作者
刘鸣
张桂萍
LIU Ming;ZHANG Gui-Ping(Department of Gynecology,the Affiliated Hospital of Qingdao University,Shandong Province,Qingdao 266000,China)
出处
《中国当代医药》
2019年第14期73-75,共3页
China Modern Medicine
关键词
基液细胞监测
阴道镜
宫颈癌前病变
Basal fluid cell monitoring
Colposcopy
Cervical precancerous lesions
