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糖尿病性视网膜病中血-视网膜屏障损伤的研究进展 被引量:7

Research progress of blood-retinal barrier injure in diabetic retinopathy
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摘要 糖尿病视网膜病(diabetic retinopathy,DR)病理过程与血-视网膜屏障(blood-retinal barrier,BRB)损伤密切相关,BRB损伤和渗透性增加,导致黄斑水肿,是2型糖尿病患者视力丢失的主要原因。BRB主要包括内屏障(iBRB)和外屏障(oBRB),其功能及生理作用不同,对环境刺激的敏感性也不同。 The pathological process of diabetic retinopathy (DR) is closely related to the damage to blood-retinal barrier (BRB).The increase of BRB damages and permeability lead to macular edema,which is the main cause of visual loss in type 2 diabetic patients.BRB mainly includes inner barrier and outer barrier,which have physiological functions,and have different sensitivities to environmental stimuli.
作者 贺鹏程(综述) 刘昌汶(综述) 尹卫东(审校) 石金凤(审校) HE Pengcheng;LIU Changwen;YIN Weidong;SHI Jinfeng(Graduate School,University of South China,Hengyang Hunan 421001,China;Major of Medical Imaging,Hengyang Medical School,University of South China,Hengyang Hunan 421001,China;Department of Biology,Hengyang Medical School,University of South China,Hengyang Hunan 421001,China;Instituteof Applied Anatomy and Reproductive Medicine,Hengyang Medical School,University of South China,Hengyang Hunan 421001,China)
出处 《临床与病理杂志》 2019年第5期1090-1094,共5页 Journal of Clinical and Pathological Research
基金 湖南省自然科学基金(14JJ2084) 南华大学大学生研究性学习和创新性试验计划(2017XJXZ037)~~
关键词 糖尿病视网膜病 血-视网膜屏障 血管内皮生长因子 糖尿病黄斑水肿 diabetic retinopathy blood-retinal barrier vascular endothelial growth factor diabetic macular edema
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