摘要
目的探讨不同中医体质老年糖尿病患者心率变异性与自主神经功能的关系。方法选取2016年3月—2017年4月在我院治疗的老年糖尿病患者250例,检测各中医体质患者SDNN、SDANN、SDNNI、RMSSD、PNN50%、LF、HF、LF/HF以及空腹血糖(FBG)、糖化血红蛋白(HbA1c)。结果总偏颇体质患者SDNN、SDANN、SDNNI、RMSSD、PNN50%、LF和HF分别为(88.37±10.02)ms、(78.82±9.44)ms、(41.14±11.43)ms、(22.28±6.53)ms、(10.03±4.33)ms、(203.38±78.23)ms^2和(122.21±80.03)ms^2,低于平和质患者(P<0.05),而LF/HF为(1.68±0.43),高于平和质患者(P<0.05);血瘀质患者SDNN、SDANN、SDNNI、RMSSD和PNN50低于气虚质、阴虚质、痰湿质、湿热质和其他型患者(P<0.05);阴虚质患者LF、HF低于气虚质、血瘀质、痰湿质、湿热质和其他型患者(P<0.05);阴虚质患者LF/HF低于气虚质、血瘀质、痰湿质、湿热质患者(P<0.05);其他型患者SDNN、SDANN、SDNNI、RMSSD、PNN50、LF、HF高于气虚质、阴虚质、痰湿质、湿热质患者(P<0.05),而LF/HF低于气虚质、阴虚质、痰湿质、湿热质患者(P<0.05);不同中医体质患者FBG、HbA1c比较差异无统计学意义(P>0.05)。结论糖尿病患者偏颇体质较平和质患者心率变异性降低,表现为交感神经张力增大,迷走神经张力降低,其平衡协调破坏。
Objective To explore the relationship between heart rate variability and autonomic nervous function in elderly diabetic patients with different constitutions of traditional Chinese medicine. Methods 250 elderly patients with diabetes mellitus in our hospital from March 2016 to April 2017 were selected;the SDANN,SDNNI,RMSSD,PN50%,LF,HF,LF/HF,fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c) were measured. Results In patients with general biased constitution,SDANN,SDNNI,RMSSD,PN50%,LF and HF were (88.37±10.02) ms,(78.82±9.44) ms,(41.14±11.43) ms,(22.28±6.53) ms,(10.03 ±4.33) ms,(203.38±78.23) ms^2 and (122.21±80.03) ms^2,which were lower than those in patients with plain constitution ( P <0.05),while LF/HF was (1.68±0.43),which was higher than that in patients with plain constitution ( P <0.05);in patients with blood stasis,SDANN,SDNNI,RMSSD and PN50 were lower than those with Qi deficiency,Yin deficiency,phlegm-dampness,damp-heat and other types ( P <0.05);LF and HF in Yin deficiency type patients were lower than those in Qi deficiency type,blood stasis type,phlegm-dampness type,damp-heat type and other types ( P <0.05);LF/HF in Yin deficiency patients was lower than that in Qi deficiency patients,blood stasis patients,phlegm-dampness patients and damp-heat patients ( P <0.05);SDANN,SDNNI,RMSSD,PN50,LF and HF in other types of patients were higher than Qi deficiency,Yin deficiency,phlegm-dampness and damp-heat ( P <0.05),while LF/HF was lower than those with Qi deficiency,Yin deficiency,phlegm-dampness and damp-heat ( P <0.05);there was no significant difference in FBG and HbA1c in patients with different constitutions of TCM ( P >0.05). Conclusion The heart rate variability of biased constitution patients with diabetes mellitus was lower than that of patients with mild constitution,manifested by increased sympathetic nerve tension,decreased vagal nerve tension and destroyed balance and coordination.
作者
黄家桓
朱文欣
夏清
李建强
HUANG Jiahuan;ZHU Wenxin;XIA Qing;LI Jianqiang(Guangzhou Yuexiu District Chinese Medicine Hospital,Guangzhou 510030, China)
出处
《广州医药》
2019年第3期80-83,共4页
Guangzhou Medical Journal
基金
广州市越秀区科技计划项目(2016-W S-014)
关键词
中医体质
糖尿病
心率变异性
自主神经功能
Chinese medicine constitution
Diabetes mellitus
Heart rate variability
Autonomic nervous function
