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冠状动脉血流储备对冠心病临界狭窄病变病人左心功能的影响 被引量:3

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摘要 目的应用血流储备分数(FFR)评价冠心病临界狭窄病变对左心功能的影响。方法筛选我院行冠状动脉造影检查的冠心病临界病变病人90例,随机分为3组,A组(FFR≥0.75不予介入干预)、B组(FFR<0.75予以介入干预)和C组(FFR<0.75不予介入干预)。分别测定所有病人术前及术后FFR,术前及术后3个月N-末端脑利钠肽原(NT-proBNP)、白介素-6(IL-6)及左室射血分数(LVEF)。结果 A组和B组FFR、LVEF水平明显优于C组,A组和B组NT-proBNP、IL-6水平明显低于C组,差异有统计学意义(P<0.05)。C组3个月内不良心血管事件(MACE)发生率明显高于A组和B组(P<0.05)。结论冠状动脉血流储备低致左心功能低下,行经皮冠状动脉介入治疗后,冠状动脉FFR增加,左心功能得到进一步改善,减少MACE发生,从而提高病人生活质量及生存率。
作者 马洪山 屈飞
出处 《中西医结合心脑血管病杂志》 2019年第8期1216-1218,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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