摘要
新生儿坏死性小肠结肠炎是新生儿常见的急性肠道炎症性坏死性疾病,其发病机制尚未完全明确,该研究从未成熟肠道生长因子水平、肠道介质对微循环的影响、多种因素所致肠道菌群异常定植、感染、喂养方式、遗传易感性及输血、脐静脉置管医疗行为等方面对NEC发病机制进展进行阐述,为临床诊疗提供依据。
Neonatal necrotizing enterocolitis(NEC)is a common acute intestinal inflammatory necrotizing neonatal disease,whose pathogenesis is still unknown.This review elaborates the research progress on the pathogenesis of NEC from the aspects including the level of immature intestinal growth factor,the effect of intestinal media on microcirculation,the abnormal colonization of intestinal flora caused by various factors,infection,feeding mode,genetic susceptibility,medical treatments such as transfusion and umbilical veins catheterization,thus providing basis for clinical diagnosis and treatment.
作者
王静
WANG Jing(Department of Pediatrics,Tianjin Medical University General Hospital,Tianjin 300052,China)
出处
《安徽医药》
CAS
2019年第6期1074-1077,共4页
Anhui Medical and Pharmaceutical Journal
