摘要
1-脱氧野尻霉素(DNJ)属于强效α-葡萄糖苷酶抑制剂,能通过降低二糖的消化和葡萄糖的吸收来降低餐后血糖,其降血糖活性好、安全性高,近年来,DNJ逐渐被用于药品和保健食品中,其分离纯化和检测方法技术研究也逐渐深入,但由于DNJ在桑叶药材中含量较低、分离纯化工艺复杂,且DNJ本身无紫外吸收,存在提取分离困难、常规检测方法不适用等问题,通过查阅国内外文献,对DNJ分离纯化技术和检测方法进行全面概述,以期为桑叶DNJ的分离纯化及检测提供参考。
1-Deoxynojirimycin is a potentα-glucosidase inhibitor.It can reduce the digestion and glucose absorption of disaccharide to reduce postprandial blood sugar.Its high safety to hypoglycemic effect.In recent years,DNJ has been gradually used in medicine and health foods.The technology of separation and purification and detection methods research also gradually deepened.However,the content of DNJ in mulberry leaves is low.The separation and purification process is complex.DNJ has no UV absorption.The extraction,separation and detection was in trouble.A comprehensive overview of DNJ isolation and purification technology and detection methods was given by reviews domestic and foreign literatures.The aim was to provide references for isolation,purification and detection of DNJ.
作者
石万银
徐剑
杨跃军
刘源才
巫岳
向诗银
唐万
SHI Wanyin;XU Jian;YANG Yuejun;LIU Yuancai;WU Yue;XIANG Shiyin;TANG Wan(Hubei Provincial Key Lab for Quality and Safety of Traditional Chinese Medicine Health Food,Jing Brand Bio-Medicine Co.,Ltd.,Huangshi,Hubei 435100,China)
出处
《农产品加工》
2019年第10期63-65,68,共4页
Farm Products Processing
