摘要
目的:研究点阵激光联合左旋维生素C在更年期女性黄褐斑患者治疗中的应用。方法:选取2017年6月-2018年12月笔者医院就诊的更年期女性黄褐斑患者60例,采用随机数字法分为观察组和对照组,每组各30例。其中对照组采取激光治疗,观察组在对照组基础上联合左旋维生素C治疗。观察两组患者治疗疗效及不良反应发生情况。结果:治疗前两组患者黄褐斑面积及颜色评分无明显差异(P>0.05);治疗后观察组患者的黄褐斑面积及颜色评分均明显低于对照组,差异有统计学意义(P<0.05)。观察组总有效率(96.67%)明显高于对照组(80.00%),差异有统计学意义(χ~2=4.68,P=0.03)。观察组总满意度(93.33%)明显高于对照组(66.67%),差异有统计学意义(χ~2=4.58,P=0.03)。观察组患者恶心、呕吐,皮肤水肿及瘢痕增生等不良反应发生率明显低于对照组(P<0.05)。结论:激光联合左旋维生素C治疗更年期女性黄褐斑具有良好的治疗效果,能够改善患者面部状况,减少不良反应,提高满意度,患者依从性较好,值得临床应用与推广。
Objective To study the application of lattice laser combined with L-vitamin C in the treatment of climacteric women with chloasma. Methods From June 2017 to December 2018, 60 cases of menopausal women with chloasma were randomly divided into observation group and control group. There were 30 cases in each group. The control group was treated with laser, and the observation group was treated with L-vitamin C on the basis of the control group.The therapeutic efficacy and adverse reactions were observed in the two groups. Results There were no significant difference in area and color score of chloasma between the two groups before treatment (P >0.05);After treatment, the area and color score of chloasma in the observation group were significantly lower than those in the control group (P <0.05). The total effective rate of the observation group (96.67%) was significantly higher than that of the control group (80.00%), and the difference was statistically significant(χ^2=4.68,P =0.03).The total satisfaction of the observation group (93.33%) was significantly higher than that of the control group (66.67%), and the difference was statistically significant(χ^2=4.58,P =0.03). The incidence of adverse reactions such as nausea, vomiting, skin edema and scar hyperplasia in the observation group was significantly lower than that in the control group (P <0.05). Conclusion Laser combined with L-vitamin C in the treatment of climacteric women with chloasma has a good therapeutic effect and can improve the facial condition of the patients,improving the facial condition of the patient, reducing the adverse reaction, and improve the satisfaction degree, and has good compliance. It is worthy of clinical application and promotion.
作者
刘素桃
刁庆春
林茂
LIU Su-tao;DIAO Qing-chun;LIN Mao(Department of Dermatology,Chongqing Traditional Chinese Medicine Hospital(Chongqing First People's Hospital),Chongqing 400011,China)
出处
《中国美容医学》
CAS
2019年第5期39-42,共4页
Chinese Journal of Aesthetic Medicine
