摘要
目的分析数字化摄影中微钙化相关乳腺癌病人的临床及影像学资料,探讨其危险因素,从而指导临床对微钙化病人的早期诊断与治疗。方法数字化摄影发现微钙化为表现的病人447例,均经活检或手术病理证实,对其临床及影像学资料进行分析,比较其在良恶性病变中的差异。结果 447例病人共检出乳腺癌93例(20.8%),其中导管内癌52例(11.6%),导管内癌伴浸润29例(6.5%),浸润性癌12例(4.7%);良性病例354例(79.2%),其中增生病腺病297例(66.4%),纤维腺瘤37例(8.3%),导管瘤10例(2.2%),导管扩张4例(0.9%),间质慢性炎4例(0.9%),硬化性腺病2例(0.4%)。恶性病变钙化与良性病变钙化在患侧位置、钙化的分布、钙化的形态、钙化的密集度、钙化的范围、乳腺影像报告和数据系统(breast imaging reporting date system,BI-RADS)分类比较差异有统计学意义(P<0.05),其中在钙化分布、钙化形态、BI-RADS分类方面差异有统计学意义(P<0.05)。结论微钙化的分布(团簇状及线样/段样)、形态(细小多形性及细线/细线分枝状)、BI-RADS分类(4类及5类)等是影响病理结果的重要因素。
Objective To analyze the clinical and radiological data of microcalcification-related breast cancer in full-field digital mammography,explore the risk factors and in order to improve the diagnosis and treatment of suspicious microcifications.Methods Clinical data and radiological characteristics were analyzed retrospectively in 447 cases of breast lesions,whose pathology were confirmed by operation.The clinical and imaging data were analyzed to compare their differences in benign and malignant lesionsResults A total of 93 cases of breast cancer were detected(20.8%),52 cases were intraductal carcinoma(11.6%),12 cases were invasivel carcinoma(4.7%),29 cases were intraductal carcinoma with infiltration(6.5%).A total of 354 cases were benign lesion(79.2%),297 cases were hyperadenosis(66.4%),37 cases were fibroadenoma(8.3%),10 cases were intraductal papilloma(2.2%),4 cases were duct ectasia(0.9%),4 cases were interstitial chronic inflammation(0.9%),2 cases were sclerosing adenopathy(0.4%).There were significant differences in microcalcifications between benign and malignant breast lesions according to position、distribution、shape、density、range and BI-RADS(P<0.05),larger differences were shown in distribution、shape and BI-RADS(P<0.05).Conclusion The distribution(grouped and linear/segmental)、shape(fine pleomorphic and fine-linear/fine-linear branch)and BI-RADS(4 and 5 category)of the microcalcification are the important factors affecting pathological results,aggressive multimodality therapy is warranted to improve prognosis.
作者
杨亚芳
段克举
刘真真
崔树德
YANG Yafang;DUAN Keju;LIU Zhenzhen(Department of Breast Surgery,Affiliated. Cancer Hospital of Zhengzhou University,Henan Cancer Hospital,Zhengzhou 450008,China)
出处
《临床外科杂志》
2019年第3期223-226,共4页
Journal of Clinical Surgery
关键词
数字化摄影
微钙化灶
乳腺癌
诊断
治疗
full-field digital mammography
microcalcification
breast cancer
diagnosis
treatment
