摘要
目的探讨联合肝脏分隔和门静脉结扎的二步肝切除术(ALPPS)Ⅰ期术后门静脉血流动力学变化与剩余肝脏体积增生的相关性。资料与方法回顾性分析成功施行ALPPS手术的6例患者的临床资料,通过彩色多普勒超声测量各时期门静脉直径、最大血流速度,分析ALPPS-Ⅰ期门静脉血流动力学变化与剩余肝体积增生的相关性。结果 6例患者术后剩余肝平均增生率为36.11%±24.08%。Pearson相关分析发现,ALPPS-Ⅰ期术后第3天门静脉主干直径(r=0.745,P=0.045)及门静脉血流量(r=0.742,P=0.046)、第5天门静脉左支直径(r=0.906,P=0.006)及血流速度(r=0.792,P=0.030)、血流量(r=0.841,P=0.018)与Ⅰ期术后剩余肝脏体积的增生率存在明显相关性。结论 ALPPS-Ⅰ期术后患者门静脉血流动力学与剩余肝脏体积的增生存在一定的相关性,其血流动力学的检测可能有助于预测ALPPS-Ⅰ期术后剩余肝体积增生情况。
Purpose To explore the correlation between portal hemodynamic changes and residual liver volume hyperplasia in patients after receiving stage I associating liver partitioning and portal vein ligation for staged hepatectomy (ALPPS). Materials and Methods Clinical data of 6 patients who received successful ALPPS were retrospectively analyzed. Color ultrasound was taken to measure diameter of portal vein and portal venous maximum velocity, the correlation between portal vein hemodynamic changes and residual liver volume hyperplasia after ALPPS-I was analyzed. Results Postoperative average residual liver volume rate of six patients was 36.11%±24.08%. Pearson correlation analysis figured out that there was obvious correlation between MPVD (r=0.745, P=0.045) and portal venous flow (r=0.742, P=0.046) the third day after ALPPS-I surgery and diameter of left portal vein (r=0.906, P=0.006), portal venous flow (r=0.792, P=0.030) and blood flow (r=0.841, P=0.018) the fifth day after surgery and hyperplasia rate of stage I postoperative residual liver volume. Conclusion There is a certain correlation between portal hemodynamics and residual liver volume hyperplasia in patients after ALPPS stage I surgery. Examination of hemodynamics might be beneficial to predicting hyperplasia of residual liver volume after ALPPS-I surgery.
作者
卢婷婷
徐邦浩
文张
郭雅
李智贤
王斯达
LU Tingting;XU Banghao;WEN Zhang;GUO Ya;LI Zhixian;WANG Sida(Department of Ultrasound, the First Affiliated Hospital of Guangxi Medical University, Nanning 53002,China)
出处
《中国医学影像学杂志》
CSCD
北大核心
2019年第4期273-276,281,共5页
Chinese Journal of Medical Imaging
基金
广西医科大学第一附属医院"优秀医学英才"科研创新能力培养项目资助
2019年广西高校中青年教师科研基础能力提升项目(2019KY0123)
关键词
肝肿瘤
肝切除术
结扎术
门静脉
超声检查
多普勒
彩色
血流动力学
肝
增生
Liver neoplasms
Hepatectomy
Ligation
Portal vein
Ultrasonography, Doppler, color
Hemodynamics
Liver
Hyperplasia
