摘要
目的分析和探讨联合检测血清SCC、CEA、CA125、CA199在宫颈癌诊断中的应用价值。方法该实验于2017年1月—2018年6月在该院进行,以方便选取此时段内收治的40例宫颈癌患者为研究组,并选择同时期健康检查者40例为参照组,检查两组患者SCC、CEA、CA125、CA199浓度,并探讨其在宫颈癌诊断中的应用价值。结果研究组患者SCC、CEA、CA125、CA199水平明显要高于参照组(t=6.866 6,P=0.000 0,t=8.976 9,P=0.000 0,t=11.352 4,P=0.000 0,t=12.257 4,P=0.000 0),并且联合监测灵敏度明显要高于单独检测,组间所存差异对比,SCC、CEA、CA125、CA199单独检测的灵敏度分别为72.5%、62.5%、60.0%、65.0%,联合检测的为95.0%,差异有统计学意义(χ~2=6.155,P=0.024、χ~2=1.017,P=0.035、χ~2=8.224,P=0.038、χ~2=4.996,P=0.015,χ~2=15.369,P=0.044)。结论对于宫颈癌的患者,联合检测血清SCC、CEA、CA125、CA199,可以提高宫颈癌诊断敏感性,效果显著,值得在今后的临床诊断治疗中应用。
Objective To analyze and explore the value of combined detection of serum SCC, CEA, CA125 and CA199 in the diagnosis of cervical cancer. Methods This experiment was conducted in our hospital from January 2017 to June 2018.40 patients with cervical cancer admitted to this period were convenient selected as the study group, and 40 patients with concurrent health examinations were selected as the reference group. Patients with SCC, CEA, CA125, CA199 concentrations, and explore its application value in the diagnosis of cervical cancer. Results The levels of SCC, CEA, CA125 and CA199 in the study group were significantly higher than those in the reference group(t=6.866 6, P=0.000 0, t=8.976 9, P=0.000 0,t=11.352 4, P=0.000 0,t=12.257 4, P=0.000 0), and the combined monitoring sensitivity was significantly higher than the individual detection, the difference between the groups, SCC, CEA, CA125, CA199 alone sensitivity of the detection was 72.5%,62.5%,60.0/%,65.0%,and the combined detection was 95.0%. The difference was statistically significant(χ^2=6.155, P=0.024,χ^2=1.017, P=0.035,χ^2= 8.224, P=0.038,χ^2=4.996, P=0.015 χ^2=15.369, P=0.044). Conclusion For patients with cervical cancer, combined detection of serum SCC, CEA, CA125, CA199 can improve the diagnostic sensitivity of cervical cancer, and the effect is significant, which is worthy of application in future clinical diagnosis and treatment.
作者
唐蕾
TANG Lei(Department of Gynecology, Xishuangbanna People's Hospital, Xishuangbanna, Yunnan Province, 666000 China)
出处
《中外医疗》
2019年第7期184-186,共3页
China & Foreign Medical Treatment
