摘要
目的应用眼前节光相干断层扫描仪(AS-OCT)及超声生物活体显微镜(UBM)评价有晶状体眼后房型人工晶状体(ICL)植入术后拱高的变化,分析2种仪器测量结果的一致性,并分析影响供高的因素。方法采用横断面研究设计,收集2017年12月至2018年3月于重庆爱尔眼科医院行ICL植入术的近视患者75例150眼的病历资料。患者术前用UBM测量前房深度(ACD)及睫状沟到沟(STS),术后1个月分别采用AS-OCT和UBM测量拱高。采用组内相关系数(ICC)分析法及Bland-Altman一致性分析法对2种仪器测量结果的可靠性进行分析。对STS距离与角膜白到白(WTW)距离的关系进行分析。结果术后1个月AS-OCT和UBM测量的拱高值分别为(0.73±0.25)mm和(0.76±0.31)mm,2种仪器测量拱高值的可靠性高(ICC=0.91),均值为0.75mm。Bland-Altman一致性分析图法显示,2种仪器测量拱高差值95%一致性区间为-0.38~0.31mm,有5个点位于95%一致性区间之外,一致性区间内差值的绝对值最大为0.31mm,超出临床可接受范围。2种设备测量的拱高值比较差异有统计学意义。术后1个月WTW对拱高有影响,线性回归方程为Y=0.1453X-0.9601(t=2.272,P<0.05)。术后1个月水平位STS距离和用过影响WTW测量间接影响拱高的测量,WTW与水平位STS距离线性回归方程为Y=0.5241X+5.3624,与垂直STS距离线性回归方程为Y=0.6134X+4.6583。结论ICL植入术后UBM测得拱高数值稍大于AS-OCT,2种仪器测量结果不能替代。STS距离的准确测量能更好指导临床医生术前精确选择合适的人工晶状体。
Objective To compare the agreement of central vault measurements between anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) in the eyes with posterior chamber phakic intraocular lens implantation and analyze the association sculus to sculus (STS) diameter and white-to-white (WTW) diameter of cornea with central vault. Methods A cross-sectional study was carried out.Medical records of 150 phakic eyes of 75 myopic patients who underwent implantable collamer lens (ICL) surgery for the correction of myopia were collected in Chongqing Aier Eye Hospital from December 2017 to March 2018.The postoperative central vault were measured with AS-OCT and UBM.Intraclass correlation coefficient (ICC) and Bland-Altman plot were used to evaluate the repeatability and agreement of the measurements between two devices.The affecting factors of central vault measurements were assessed. Results Mean central vault in the 150 phakic eyes after ICL surgery was (0.73±0.25)mm by AS-OCT and (0.76±0.31)mm by UBM,respectively with the ICC of 0.91 for the measurements of AS-OCT and UBM.Bland-Altman analysis showed that the 95% limits of agreement of central vault measurements were -0.38-0.31 mm between the two devices.Five values were beyond the 95% consistency interval,and the maximum absolute value of the difference was is 0.31 mm,which was beyond the clinical acceptable range,showing an non-interchangeable difference in the central vault measurements between the devices in ICL implanted eyes.WTW was a affecting factor for vault with a regression equation of Y = 0.145 3 X - 0.960 1 ( t =2.272, P <0.05).Horizontal and vertical STS were the indirect affecting factors for vault by the association with WTW with the regression equation of Y = 0.524 1 X + 5.362 4 and Y = 0.613 4 X + 4.658 3 ,respectively. Conclusions Central vault measured by UBM is higher that than AS-OCT after ICL surgery,and the measurements are uninterchangeable between the two devices.Accurate measurement of STS distance is essential fo
作者
薛艳珍
周奇志
Xue Yanzhen;Zhou Qizhi(Aier School of Ophthalmology,Central South University,Changsha Aier Eye Hospital,Changsha 410000,China;Chongqing Aier Eye Hospital,Chongqing 400000,China)
出处
《中华实验眼科杂志》
CAS
CSCD
北大核心
2019年第4期287-291,共5页
Chinese Journal Of Experimental Ophthalmology
