摘要
目的从力学角度探讨有晶状体眼后房型人工晶状体(pIOL)植入术后不同时间拱高的影响因素。方法回顾性病例系列研究。收集2018年6月至2020年6月于青岛大学附属医院眼科行有晶状体眼pIOL植入术的123例近视眼患者资料,其中男性37例,女性86例,年龄(24.74±5.58)岁。单眼手术者纳入术眼、双眼手术者纳入术前超声生物显微镜(UBM)影像更清晰的1只眼进行研究。术前在UBM下观察眼前节结构并采用图像分析软件Image J测量虹膜、睫状体形态学参数,包括虹膜跨度(IS)、虹膜膨隆度(IC)、虹膜-睫状体接触距离(ICCD)及虹膜-晶状体接触距离(ILCD)等,并按ICCD从0起每0.36 mm范围将患者分为Q1、Q2、Q3组;采用光学生物测量仪测量晶状体厚度,采用Pentacam眼前节分析系统测量角膜水平径和前房深度;记录植入的pIOL尺寸型号。于术后1周、3个月、1年使用相干光层析成像术(OCT)测量拱高。采用Pearson相关分析、Spearman相关分析以及多重线性回归分析术前眼前节参数对术后不同时间拱高的影响,重复测量方差分析用于比较术后不同时间的拱高。结果术后1周、3个月、1年的拱高分别为(723±265)、(642±255)、(613±280)μm,差异有统计学意义(F=50.143,P<0.001)。术后1年内拱高持续下降,下降总量为(122±86)μm,其中术后1周至术后3个月下降(69±98)μm;术后3个月至术后1年下降(52±54)μm。回归模型显示pIOL尺寸型号、ILCD与术后1周的拱高呈正相关,晶状体厚度、IS、IC与术后1周的拱高呈负相关(调整R^(2)=0.404,P<0.001);pIOL尺寸型号、ILCD与术后3个月的拱高呈正相关,IS、IC与术后3个月的拱高呈负相关(调整R^(2)=0.342,P<0.001);pIOL尺寸型号与术后1年的拱高呈正相关,IS、IC与术后1年的拱高呈负相关(调整R^(2)=0.661,P<0.001)。Q3组术后各时间点的拱高均高于Q1组,Q2组术后1年的拱高高于Q1组。结论pIOL较大、IS短、ILCD和ICCD大可能与术后早�
Objective To investigate the impact of the iris and ciliary body morphology on the central vault after phakic posterior chamber intraocular lens(pIOL)implantation.Methods This research was based on the retrospective analysis of 123 patients(123 eyes)who underwent pIOL implantation in the Department of Ophthalmology,Affiliated Hospital of Qingdao University between June 2018 and June 2020.The anterior segment structure was observed with an ultrasound biomicroscope before surgery,and all morphological parameters of the iris and ciliary body were measured manually using the ImageJ software,including iris span(IS),iris convexity(IC),iris-ciliary body contact distance(ICCD)and iris-lens contact distance(ILCD).The ICCD was divided into Q1,Q2 and Q3 groups according to the equidistant distance of 0.36 mm.The lens thickness was measured with the IOLMaster.The horizontal corneal diameter and anterior chamber depth were measured using the Pentacam.The central vaults were measured by optical coherence tomography at 1 week,3 months and 1 year after surgery.The relationships between vault values and preoperative parameters of the anterior segment were evaluated using the Pearson correlation analysis,Spearman correlation analysis,and multiple linear regression.The repeated measures ANOVA was applied to identify changes of vault values over time.Results The mean values of the vaults at 1 week,3 months and 1 year after surgery were(723±265)μm,(642±255)μm and(613±280)μm,respectively.The difference among them was statistically significant(F=50.143,P<0.001).The vaults continued to decline within 1 year after pIOL implantation,and the total decline was(122±86)μm.The vaults declined by(69±98)μm from postoperative 1 week to 3 months and by(52±54)μm from postoperative 3 months to 1 year.The regression formula showed that the pIOL size and ILCD were positively related with the vault,while the LT,IS and IC were negatively related with the vault at 1 week postoperatively(adjusted R²=0.404,P<0.001).The pIOL size and ILCD were
作者
彭慧
王芳
李金键
李江峰
沈晓丽
刘桂波
潘星慧
侯辰亭
易雯丹
王青
Peng Hui;Wang Fang;Li Jinjian;Li Jiangfeng;Shen Xiaoli;Liu Guibo;Pan Xinghui;Hou Chenting;Yi Wendan;Wang Qing(Department of Ophthalmology,the Affiliated Hospital of Qingdao University,Qingdao 266003,China;Department of Ophthalmology,Weihai Municipal Hospital,Weihai 264200,China;College of Public Health,Qingdao University,Qingdao 266071,China)
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2022年第8期615-623,共9页
Chinese Journal of Ophthalmology
