摘要
目的观察自拟降脂方联合运动疗法干预部队官兵高脂血症的临床有效性和安全性。方法将2016年7月—2018年10月疗养的符合研究标准的高脂血症官兵150例,随机分为自拟降脂方组、单纯运动疗法组、联合治疗组,每组50例。分别于治疗前,治疗后8、12、16、20周观察中医症候积分,体重指数(BMI),血脂变化情况,并判定疗效及安全性。结果联合治疗组治疗后不同时点BMI均低于自拟降脂方组和单纯运动疗法组,中医证候及血脂指标总有效率均高于自拟降脂方组和单纯运动疗法组(P <0. 05)。3组治疗后肝肾功能比较差异无统计学意义(P>0. 05)。结论自拟降脂方结合运动疗法干预部队官兵高脂血症,可有效改善BMI,在中医证候和血脂改善疗效评定方面效果显著,且安全性较高。
Objective To observe clinical efficacy and safety of self-made reducing blood fat decoction combined with exercise therapy in intervention of officers and soldiers with hyperlipidemia. Methods A total of 150 officers and soldiers with hyperlipidemia who had being resting therapy during July 2016 and October 2018, were randomly divided into self-made reducing blood fat decoction group, simple exercise therapy group and combined treatment group ( n =50 in each group). Changes of traditional Chinese medicine (TCM) symptom scores, body mass index (BMI) and blood lipid levels before and in 8 th , 12 th , 16 th and 20 th weeks after treatment were observed, and efficacy and safety were determined. Results At different time points after treatment, in combined treatment group, BMI levels were significantly lower, while TCM symptom scores, blood lipid indexes and the total effective rates were significantly higher than those in self-made reducing blood fat decoction and simple exercise therapy groups ( P <0.05). There were no significant differences in liver and kidney functions after treatment among three groups ( P >0.05). Conclusion Self-made reducing blood fat decoction combined with exercise therapy may effectively improve BMI in officers and soldiers with hyperlipidemia. It has significant effect in TCM syndromes, lipid improvement and efficacy evaluation with good safety.
作者
张宝珍
黄力平
董林森
陈立柱
王秋岩
孙璐
张海鹏
陈银海
张凯
ZHANG Bao-zhen;HUANG Li-ping;DONG Lin-sen;CHEN Li-zhu;WANG Qiu-yan;SUN Lu;ZHANG Hai-peng;CHEN Yin-Hai;ZHANG Kai(Health Management Center, Tianjin Sanatorium of Beijing Military Command, Tianjin 300191, China;School of Health and Sports Science, Tianjin College of Physical Education, Tianjin, 300381, China;Department of Acupuncture and Physiotherapy, Tianjin Public Security Hospital, Tianjin 300042, China)
出处
《解放军医药杂志》
CAS
2019年第4期104-108,共5页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
军委后勤保障部卫生局保健专项课题面上项目(16BJZ46)
关键词
中药疗法
运动疗法
高脂血症
军事人员
Drug therapy
Exercise therapy
Hyperlipidemia
Military personnel
