摘要
目的:观察支持性心理治疗与帕罗西汀合并米氮平联合对难治性抑郁症的效果。方法:收治难治性抑郁患者60例,分对照组(进行帕罗西汀合并米氮平治疗)和试验组(在对照组基础上联合支持性心理治疗),比较治疗效果和抑郁评分。结果:试验组临床总有效率(93.33%)显著较对照组(73.33%)高,差异有统计学意义(P<0.05);治疗8周后两组汉密尔顿抑郁量表(HAMD)评分均降低,且试验组较对照组低,差异有统计学意义(P<0.05)。结论:在难治性抑郁症治疗中,支持性心理治疗同帕罗西汀合并米氮平联合治疗效果更突出,较单纯药物治疗更利于患者恢复。
Objective:To observe the effect of supportive psychotherapy combined with paroxetine and mirtazapine in the treatment of refractory depression.Methods:60 patients with refractory depression were selected.They were divided into the control group(treated with paroxetine combined with mirtazapine)and the experimental group(combined with supportive psychotherapy on the basis of the control group)equally.We compared the therapeutic effect and depression score.Results:The total clinical effective rate(93.33%)of the experimental group was significantly higher than that of the control group(73.33%),P<0.05 with statistical difference.After 8 weeks of treatment,the scores of the two groups were decreased,and the experimental group was lower than the control group,P<0.05 with statistical difference.Conclusion:In the treatment of refractory depression,supportive psychotherapy combined with paroxetine and mirtazapine is more effective,which is more conducive to the recovery of patients than drug therapy alone.
作者
孙玉梅
Sun Yumei(Rongjun Hospital of Linyi City,Shandong Province 276000)
出处
《中国社区医师》
2019年第10期62-63,共2页
Chinese Community Doctors