摘要
目的探讨宫颈癌术后调强放疗中两种不同固定体位对肠道受照剂量和放疗副反应的影响.方法2011年—2016年符合入组条件行调强放射治疗的宫颈癌术后患者158例,随机分为两组,仰卧位组(n=77)采用真空垫固定,俯卧位组(n=81)采用碳纤维腹板固定,处方剂量:45~50 Gy/23~25次,对两组患者肠道受照剂量、放射性肠炎和放射性皮炎发生率进行比较.结果仰卧位组和俯卧位组患者0-1级、2-3级放射性肠炎发生率分别为59.7%、40.3%和76.5%、23.5%,俯卧位组2-3级放射性肠炎发生率低于仰卧位组(P=0.024).仰卧位组和俯卧位组患者0-1级、2-3级放射性皮炎发生率分别为62.3%、37.7%和54.3%、45.7%,两组比较差异无统计学意义(P=0.309).结论宫颈癌术后调强放疗,俯卧位体位固定可减少患者小肠的受照射体积,降低严重(2-3级)放射性肠炎的发生率.
Objective To compare radiation dose of intestine and side effects between two different body positions during intensity modulated radiation therapy(IMRT)for cervical cancer.Methods 158 eligible postoperative cervical cancer patients between 2011 and 2016 were randomly divided into two groups:77 cases in supine position,fixed with vacuum cushion,and 81 cases in prone position,fixed with carbfiber board.Both groups received a dose 45-50 Gy/23-25 times,and radiation dose of intestine,radiation enteritis and dermatitis between two groups were compared.Results Incidence of 0-1 and 2-3 grade radiation enteritis for supine position and prone position were 59.7%,40.3%and 76.5%,23.5%respectively,and 2-3 grade radiation enteritis for prone position was significantly lower than supine position(P=0.024).Incidence of 0-1 and 2-3 grade radiation dermatitis for two groups were 62.3%,37.7%and 54.3%,45.7%respectively,with no significant difference(P=0.309).Conclusion For postoperative cervical cancer patients who undergoing IMRT,prone position could reduce enteral irradiated volume and so decrease the incidence of severe radiation enteritis.
作者
芦玉婷
孟庆红
王坚
孙志强
汪建林
武艾芳
Author: LU Yu-ting;MENG Qing-hong;WANG Jian;SUN Zhi-qiang;WANG Jian-lin;WU Ai-fang(Department of Radiotherapy,the Second Hospital of Changzhou,Changzhou,Jiangsu,213003,China)
出处
《中国血液流变学杂志》
CAS
2018年第3期348-351,共4页
Chinese Journal of Hemorheology
关键词
调强放疗
碳纤维腹板
真空垫
小肠体积
同步放化疗
intensity modulated radiation therapy
belly board device
vacuum spacer
small bowel volume
concurrent chemoradiotherapy
