摘要
目的探讨结直肠癌患者拒绝接受遗传性肠癌相关基因筛查的原因,为采取措施提高患者及家属遗传筛查及肠癌筛查率提供依据。方法采用立意取样法,选取2017年8-12月在广州某3家三级甲等医院结直肠外科诊治的初次罹患结直肠癌,且拒绝参加遗传性肠癌基因筛查项目的14例患者为研究对象。采用质性研究中现象学的方法对患者进行非结构性访谈,采用Colaizzi分析法对资料进行整理和分析。结果本研究共提炼出4个主题:知识缺乏;逃避事实,心理防御机制过强;对现有医学技术无信心,不信任医务人员;担心带来不良影响。结论医护人员应深入了解患者拒绝进行基因筛查的原因,开展遗传咨询,促进高危患者基因筛查率,提高遗传性肠癌的确诊率。
Objective To explore the reasons why colorectal cancer patients refuse to accept genetic screening associated with hereditary bowel cancer and to provide a basis for further measures to improve the rate of genetic and bowel cancer screening in patients and families. Methods Totally 14 patients first diagnosed of colorectal cancer from 3 Class Ⅲ Grade A hospitals in Guangzhou between August and December 2017 and refused to accept genetic screening associated with bowel cancer were selected by purposive sampling. The phenomenological method in qualitative studies were used for unstructured interview in these patients. The data were organized and analyzed with Colaizzi analysis. Results This study boiled down to 4 topics: lack of knowledge, avoidance of facts, strong psychological defense mechanism, lack of confidence in existing medical technologies, distrust on medical workers and worries about negative effects. Conclusions Medical and nursing workers shall explore further the reasons why the patients refuse to accept genetic screening, provide genetic counselling, improve the rate of genetic screening in high-risk patients, and improve the diagnosis rate of hereditary bowel cancer.
作者
吴晓丹
方雪梅
吴亮正
姜武
贾书敏
潘志忠
Wu Xiaodan;Fang Xuemei;Wu Liangzheng;Jiang Wu;Jia Shumin;Pan Zhizhong(Department of Colorectum,Sun Yat-sen University Cancer Center,Guangzhou 510060,China;Head and Neck Service,Sun Yat-sen University Cancer Center,Guangzhou 510060,China;Class 155-3,Grade 2015,Hu'nan Polytechnic of Environment and Biology,Hengyang 421005,China;School of Nursing,Sun Yat-sen University,Guangzhou 510080,China)
出处
《中华现代护理杂志》
2018年第36期4378-4381,共4页
Chinese Journal of Modern Nursing
基金
国家重点研发计划资助(2017YFC0908202).
关键词
结直肠肿瘤
遗传
基因筛查
原因
质性研究
Colorectal neoplasms
Heredity
Genetic screening
Reasons
Qualitative study
