摘要
通过高效液相色谱法检测β-熊果苷降解产物氢醌,考察温度、含量、pH、放置时间以及表皮葡萄球菌、表皮细胞等因素对β-熊果苷稳定性的影响。结果表明,β-熊果苷水溶液在pH=5,温度为40 ℃时相对比较稳定,pH=3时相对不稳定,且随着放置时间的延长,β-熊果苷分解产生的氢醌越多。同时研究发现将表皮葡萄球菌在不同含量的β-熊果苷培养液中培养24 h,β-熊果苷均未分解生成氢醌,说明表皮葡萄球菌不会导致β-熊果苷分解产生氢醌。将表皮细胞放在不同含量的β-熊果苷培养液中培养24 h,有氢醌生成,说明表皮细胞会促进β-熊果苷的分解。进一步研究发现,β-熊果苷原料在不同温度、湿度下均很稳定。在β-熊果苷中加入维生素C、珍珠粉,β-熊果苷的稳定性会下降。
The β-arbutin degradation product hydroquinone was detected by high performance liquid chromatography to investigate the effects of temperature, content, pH, standing time, Staphylococcus epidermidis and epidermal cells on the stability of β-arbutin. Results show that β-arbutin aqueous solution remains relatively stable under pH of 5 and temperature of 40 ℃, and β-arbutin becomes unstable under pH of 3. The longer the standing time is, the more hydroquinone is produced by the decomposition of β-arbutin. At the same time, it is found that Staphylococcus epidermidis cultured in different content of β-arbutin for 24 h, and β-arbutin does not decompose into hydroquinone, indicating that Staphylococcus epidermidis does not lead to the decomposition of β-arbutin. The epidermal cells were cultured in the medium containing different content of β-arbutin for 24 h, and hydroquinone was generated, indicating that the epidermal cells promote the decomposition of β-arbutin. Further studies show that β-arbutin materials are very stable at different temperatures and humidity. But adding vitamin C and pearl powder into β-arbutin can redu ce the stability of β-arbutin.
作者
闫秀芳
张鑫
范倩文
YAN Xiu-fang;ZHANG Xin;FAN Qian-wen(R&D, Shanghai Jahwa United Co.,Ltd., Shanghai 200080,China)
出处
《日用化学工业》
CAS
CSCD
北大核心
2019年第3期178-182,198,共6页
China Surfactant Detergent & Cosmetics
关键词
化妆品美白原料
β-熊果苷
高效液相色谱法
氢醌
稳定性
cosmetic whitening ingredient
β-arbutin
high performance liquid chromatography
hydroquinone
stability
