摘要
目的探讨急性有机磷中毒致中间综合征(IMS)的危险因素及预后影响因素。方法回顾性分析2015年2月—2017年3月153例急性有机磷中毒患者的临床资料,采用多因素Logistic回归性分析急性有机磷中毒致IMS的危险因素及预后影响因素。结果多因素Logistic回归分析结果显示,抬头困难、合并基础疾病、白细胞计数是急性有机磷中毒致IMS的独立危险因素(P<0.05);洗胃时间、血流灌注及急性生理学与慢性健康状况评分系统Ⅱ评分是影响急性有机磷中毒并发IMS患者预后的独立危险因素(P<0.05)。结论在急性有机磷中毒患者的临床诊治的过程中,应密切关注上述影响因素,对IMS进行早期规避或预防,提高患者预后生存质量。
Objective To investigate risk factors and influencing factors of prognosis in patients with intermediate syndrome (IMS) caused by acute organophosphate poisoning. Methods Clinical data of 153 patients with acute organophosphorus poisoning during February 2015 and March 2017 was retrospectively analyzed. Risk factors and influencing factors of prognosis in IMS patients caused by acute organophosphorus poisoning were analyzed by multivariate Logistic regression. Results Multivariate logistic regression analysis showed that difficulty in raising head difficulty, combined with underlaying diseases and white blood cell count were independent risk factors for IMS patients induced by acute organophosphorus poisoning ( P <0.05). Gastric lavage time, blood perfusion and acute physiology and chronic health evaluation systemⅡ score were independent risk factors for prognosis of patients with acute organophosphorus poisoning complicated with IMS ( P <0.05). Conclusion Clinicians should pay more attention to the above influencing factors and avoid or prevent them as early as possible so as to improve the prognosis and life quality of patients in the process of clinical diagnosis and treatment of patients with acute organophosphorus poisoning.
作者
童武进
黄星
汤彦
吉春风
陆伟荣
TONG Wu-jin;HUANG Xing;TANG Yan;JI Chun-feng;LU Wei-rong(Emergency Department, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai 201700, China)
出处
《解放军医药杂志》
CAS
2019年第3期91-95,共5页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
上海市卫生和计划生育委员会科研项目资助(20164Y0101)
关键词
有机磷化合物
中毒
中间综合征
危险因素
预后
Organophosphorus compounds
Poisoning
Intermediate syndrome
Risk factors
Prognosis
