摘要
目的:分析脊柱骨折患者采用复元活血汤加减治疗的临床疗效以及对患者疼痛程度、凝血功能与术后炎症因子产生的影响。方法:于我院2014年12月-2017年12月收治的脊柱骨折患者中选取80例,随机分为两组,对照组行常规治疗,观察组在对照组基础上采用复元活血汤治疗,对比两组治疗前后视觉模拟疼痛(VAS)评分、D-二聚体含量(D-D)、纤维蛋白原(FIB)、血小板计数(PLT)等凝血功能指标与高迁移率族蛋白1(HMGB1)、降钙素原(PCT)、肿瘤坏死因子-α(TNF-α)、反应蛋白(CRPC)等血清炎性因子水平变化情况。结果:观察组治疗后第3 d的VAS评分、D-D、FIB、PLT等凝血功能指标水平与HMGB1、PCT、TNF-α、CRP等血清炎性因子水平均低于对照组,组间差异有统计学意义,P <0.05。结论:脊柱骨折患者采用复元活血汤加减治疗的临床疗效显著,有利于减轻患者疼痛程度,改善术后凝血功能与机体炎症状态,值得推广。
Objective: To analyze clinical efficacy of the Fuyuan Huoxue decoction (复元活血汤) on inflammatory factors, coagulation function and pain level in patients with spinal fracture after surgery. Methods: December 2014-December 2017, 80 cases were divided into 2 groups. The control group was given conventional treatment;and the observation group was given the Fuyuan Huoxue decoction more. Results: After treatment, the VAS score, D-D, FIB, PLT, etc. and HMGB1, PCT, TNF-α, CRP and other levels in the observation group were lower than the control group, P < 0.05. Conclusion: The Fuyuan Huoxue decoction on inflammatory factors, coagulation function and pain level in patients with spinal fracture after surgery show a good effect, can alleviate the pain level of patients and improve the postoperative coagulation function and the inflammatory state of the body, which is worth promoting.
出处
《中医临床研究》
2019年第5期7-9,共3页
Clinical Journal Of Chinese Medicine
关键词
脊柱骨折
复元活血汤
疼痛程度
凝血功能
术后炎症因子
Spinal fracture
The Fuyuan Huoxue decoction
Pain degree
Coagulation function
Postoperative inflammatory factor
